Evidence map›Paper›PMID 29636754›Full record

ArticleFrontiers in immunology2018

Macrophage Transactivation for Chemokine Production Identified as a Negative Regulator of Granulomatous Inflammation Using Agent-Based Modeling.

Daniel Moyo, Lynette Beattie, Paul S Andrews, John W J Moore, Jon Timmis, Amy Sawtell, Stefan Hoehme, Adam T Sampson, Paul M Kaye

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Agent-based models of inflammation in translational systems biology: A decade later.Wiley interdisciplinary reviews. Systems biology and medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Daniel MoyoCentre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, York, United Kingdom.
Lynette BeattieCentre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, York, United Kingdom.
Paul S AndrewsDepartment of Electronics, University of York, York, United Kingdom.
John W J MooreCentre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, York, United Kingdom.
Jon TimmisDepartment of Electronics, University of York, York, United Kingdom.
Amy SawtellCentre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, York, United Kingdom.
Stefan HoehmeInstitute for Computer Science, University of Leipzig, Leipzig, Germany.
Adam T SampsonDivision of Computing and Mathematics, Abertay University, Dundee, United Kingdom.
Paul M KayeCentre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, York, United Kingdom.
University of York · GBHull York Medical School · GBAbertay University · GBLeipzig University · DE

Funding

Medical Research Council G0400786Medical Research Council G1000230National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/C013205/1Wellcome TrustWellcome Trust WT106203
6 · The paper itself

Abstract

Cellular activation

Indexed as

AnimalsCells, CulturedChemokinesDisease Models, AnimalGene Expression ProfilingGranulomaHumansInflammationKupffer CellsLeishmania donovaniLeishmaniasis, VisceralLiverMacrophagesMiceMice, Inbred C57BLNatural Killer T-CellsChemokinesagent-based modelingcomputational immunologygranulomasinflammationkupffer cellsLeishmanialivernatural killer T cells

Identifiers

PMID29636754
PMCPMC5880939
OpenAlexW2790992127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.