Evidence map›Paper›PMID 29636681›Full record

ArticleFrontiers in pharmacology2018

Mechanisms of BK Channel Activation by Docosahexaenoic Acid in Rat Coronary Arterial Smooth Muscle Cells.

Ling-Ling Qian, Man-Qing Sun, Ru-Xing Wang, Tong Lu, Ying Wu, Shi-Peng Dang, Xu Tang, Yuan Ji, Xiao-Yu Liu, Xiao-Xi Zhao and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Empagliflozin Induces Vascular Relaxation in Rat Coronary Artery Due to Activation of BK Channels.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Ling-Ling QianDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Man-Qing SunDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Ru-Xing WangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Tong LuDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.
Ying WuDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Shi-Peng DangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Xu TangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Yuan JiDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Xiao-Yu LiuDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Xiao-Xi ZhaoDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical UniversityWuxi, China.
Wen WangState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Qiang ChaiDepartment of Physiology, Institute of Basic Medicine, Shandong Academy of Medical Sciences, Jinan, China.
Min PanDepartment of Cardiology, Affiliated Hospital Nantong University, Nantong, China.
Fu YiDepartment of Cardiovascular Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Dai-Min ZhangNanjing First Hospital, Nanjing, China.
Hon-Chi LeeDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.
Nanjing Medical University · CNWuxi People's Hospital · CNMayo Clinic in Arizona · USAffiliated Hospital of Nantong University · CNNanjing University · CNShandong First Medical University · CNXijing Hospital · CN

Funding

Type 2 Diabetes and Vascular BK Channel RegulationR01HL074180 · NHLBI · MAYO CLINIC ROCHESTER · PI LEE, HON-CHI · 2003 to 2018
$4.8M
Endothelial BK Channel Regulation by Caveolae TargetingR01HL080118 · NHLBI · MAYO CLINIC ROCHESTER · PI LEE, HON-CHI · 2006 to 2010
$1.8M
NHLBI NIH HHS R01 HL074180NHLBI NIH HHS R01 HL080118
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BK channelcoronary arterial smooth muscle cellscytosolic calciumdocosahexaenoic acidPLC–IP3 signal pathway

Identifiers

PMID29636681
PMCPMC5881017
OpenAlexW2794813900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.