Evidence map›Paper›PMID 29636618›Full record

ArticleTherapeutics and clinical risk management2018

Is ischemia-modified albumin a reliable tool for the assessment of acute pancreatitis?

Abdurrahman Sahin, Semra Turkoglu, Nurettin Tunc, Deccane Duzenci, Ozgen Arslan Solmaz, Ibrahim Halil Bahcecioglu, Mehmet Yalniz

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Metabolic signature of COVID-19 progression: potential prognostic markers for severity and outcome.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  4. Article
  5. Can Ischemia Modified Albumin (IMA) Levels Be a Predictor of Acute Pancreatitis?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Abdurrahman SahinMedicine Faculty, Department of Gastroenterology, Firat University, Elazig, Turkey.
Semra TurkogluDepartment of Nutrition and Dietetics, Health Sciences Faculty, Firat University, Elazig, Turkey.
Nurettin TuncMedicine Faculty, Department of Gastroenterology, Firat University, Elazig, Turkey.
Deccane DuzenciDepartment of Internal Medicine, Elazig Education and Training Hospital, Elazig, Turkey.
Ozgen Arslan SolmazDepartment of Pathology, Elazig Education and Training Hospital, Elazig, Turkey.
Ibrahim Halil BahceciogluMedicine Faculty, Department of Gastroenterology, Firat University, Elazig, Turkey.
Mehmet YalnizMedicine Faculty, Department of Gastroenterology, Firat University, Elazig, Turkey.
Fırat University · TRElazığ Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOxidative stress has been implicated in several disorders, including acute pancreatitis (AP). Ischemia-modified albumin (IMA), which reflects the ability to bind cobalt, has been found to be elevated in conditions of oxidative stress and tissue hypoxia. This study examined IMA and adjusted IMA levels in patients with AP, and examined the associations of IMA and adjusted IMA levels to the severity of AP. PATIENTS AND

methodsA total of 42 consecutive patients with AP and 43 age- and sex-matched control subjects were enrolled. Serum samples were obtained from patients with AP on admission as well as 48-72 hours after hospitalization, and from the controls, at the time of enrollment. Adjusted IMA was calculated by multiplying the IMA value of each patient with the ratio of the patient's albumin value and the median albumin value of the study population. The severity of AP was assessed according to the modified Atlanta classification, and the patients were divided into 2 groups: mild AP and severe AP.

resultsThe serum IMA and adjusted IMA values of patients with AP on admission and those of the controls did not differ (

conclusionIt was shown that IMA and adjusted IMA levels rise with the progression of AP. Lower levels of adjusted IMA predict the severity of AP. Further studies with serial measurements of IMA are warranted to explore the indicative role of IMA in the course of AP.

Indexed as

acute pancreatitisadjusted ischemia modified albuminischemia modified albuminseverity

Identifiers

PMID29636618
PMCPMC5881528
OpenAlexW2795301871

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.