ArticleScientific reports2018
Satiation state-dependent dopaminergic control of foraging in Drosophila.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 81 citations in OpenAlex.
- Systematic analysis of mushroom body-innervating dopaminergic neuron activity in different physiological states in Drosophila.Biomedical journal · 2026Article
- Conserved dopaminergic system in Octopus minor: molecular characterization and spatial expression.Brain structure & function · 2026Article
- Metaplastic neuronal state transition regulates species-specific interoceptive processing inbioRxiv : the preprint server for biology · 2026Article
- Contrasting whole-genome diversity patterns and adaptation in honeybees from two southern European glacial refugia.iScience · 2026Article
- From retina to brain: retinal dysfunction and dopaminergic neurodegeneration inFrontiers in cell and developmental biology · 2026Article
- Dual roles ofiScience · 2025Article
- Hunger Recruits a Parallel Circuit Encoding Alcohol Reward.bioRxiv : the preprint server for biology · 2025Article
- Neurofibromin Deficiency Alters the Patterning and Prioritization of Motor Behaviors in a State-Dependent Manner.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The role of dopamine in foraging decisions in social insects.Frontiers in insect science · 2025Review
- Article
- Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion.PLoS biology · 2024Article
- Review
- Phototaxis is a satiety-dependent behavioral sequence in Hydra vulgaris.The Journal of experimental biology · 2024Article
- Neurofibromin deficiency alters the patterning and prioritization of motor behaviors in a state-dependent manner.bioRxiv : the preprint server for biology · 2024Article
- Preference of position in the proximity of various sugars revealed by location analysis of Drosophila melanogaster.Scientific reports · 2024Article
- Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants.Cell · 2023Article
- Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila.Nature communications · 2023Article
- Behavioral dissection of hunger states ineLife · 2023Article
- Food memory circuits regulate eating and energy balance.Current biology : CB · 2023Article
- Effect of aminergic signaling on the humoral innate immunity response ofFrontiers in physiology · 2023Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Hunger evokes stereotypic behaviors that favor the discovery of nutrients. The neural pathways that coordinate internal and external cues to motivate foraging behaviors are only partly known. Drosophila that are food deprived increase locomotor activity, are more efficient in locating a discrete source of nutrition, and are willing to overcome adversity to obtain food. We developed a simple open field assay that allows flies to freely perform multiple steps of the foraging sequence, and we show that two distinct dopaminergic neural circuits regulate measures of foraging behaviors. One group, the PAM neurons, functions in food deprived flies while the other functions in well fed flies, and both promote foraging. These satiation state-dependent circuits converge on dopamine D1 receptor-expressing Kenyon cells of the mushroom body, where neural activity promotes foraging independent of satiation state. These findings provide evidence for active foraging in well-fed flies that is separable from hunger-driven foraging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.