ArticleJournal of lipid research2018
Adipocyte-specific DKO of Lkb1 and mTOR protects mice against HFD-induced obesity, but results in insulin resistance.
Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue.Nature metabolism · 2024Article
- Ginsenoside RgNutrients · 2024Article
- Honokiol ameliorates angiotensin II-induced cardiac hypertrophy by promoting dissociation of the Nur77-LKB1 complex and activating the AMPK pathway.Journal of cellular and molecular medicine · 2024Article
- The role of liver kinase B1 in tumor progression through regulation of lipid metabolism.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022Review
- LKB1 on POMC neurons affect the formation of diet-induced obesity by regulating the expression of HDAC1.Genes & genomics · 2022Article
- The regulation of adipocyte growth in white adipose tissue.Frontiers in cell and developmental biology · 2022Review
- LKB1 Regulates Goat Intramuscular Adipogenesis Through Focal Adhesion Pathway.Frontiers in physiology · 2021Article
- miR-424 Promotes Bovine Adipogenesis Through an Unconventional Post-Transcriptional Regulation ofFrontiers in genetics · 2020Article
- Elucidating the role of Lkb1 and mTOR in adipose tissue.Adipocyte · 2019Article
- Conditional Knockout of Raptor/mTORC1 Results in Dentin Malformation.Frontiers in physiology · 2019Article
- Chronic oral rapamycin decreases adiposity, hepatic triglycerides and insulin resistance in male mice fed a diet high in sucrose and saturated fat.Experimental physiology · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Liver kinase B1 (Lkb1) and mammalian target of rapamycin (mTOR) are key regulators of energy metabolism and cell growth. We have previously reported that adipocyte-specific KO of Lkb1 or mTOR in mice results in distinct developmental and metabolic phenotypes. Here, we aimed to assess how genetic KO of both Lkb1 and mTOR affects adipose tissue development and function in energy homeostasis. We used
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.