Evidence map›Paper›PMID 29636346›Full record

ArticleJournal of the American Heart Association2018

Association of "Elevated Blood Pressure" and "Stage 1 Hypertension" With Cardiovascular Mortality Among an Asian Population.

Mohammad Talaei, Naeimeh Hosseini, Angela S Koh, Jian-Min Yuan, Woon-Puay Koh

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

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  18. Cardiovascular events associated with stage 1 hypertension in Asian populations: is this a more critical issue in younger adults?Hypertension research : official journal of the Japanese Society of Hypertension · 2019
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  19. Should blood pressure ≥130/80 mm Hg be considered as a cardiovascular disease?Journal of clinical hypertension (Greenwich, Conn.) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Mohammad TalaeiHealth Services and Systems Research, Duke-NUS Medical School, Singapore woonpuay.koh@duke-nus.edu.sg mohammad.talaei@u.nus.edu.
Naeimeh HosseiniDuke-NUS Medical School, Singapore.
Angela S KohDuke-NUS Medical School, Singapore.
Jian-Min YuanDivision of Cancer Control and Population Sciences, UPMC Hillman Cancer, University of Pittsburgh, PA.
Woon-Puay KohHealth Services and Systems Research, Duke-NUS Medical School, Singapore woonpuay.koh@duke-nus.edu.sg mohammad.talaei@u.nus.edu.
Duke-NUS Medical School · SGNational Heart Centre Singapore · SGNational University of Singapore · SGUniversity of Pittsburgh · US

Funding

Prospective studies of cancer etiology and prevention in Shanghai and SingaporeR01CA144034 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2010 to 2014
$7.0M
Cancer epidemiology cohorts in Shanghai and Singapore UM1CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2014 to 2018
$4.3M
The Singapore Chinese Health StudyU01CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2019 to 2019
$150k
NCI NIH HHS R01 CA144034NCI NIH HHS U01 CA182876NCI NIH HHS UM1 CA182876
6 · The paper itself

Abstract

backgroundThe new American College of Cardiology/American Heart Association high blood pressure (BP) guidelines in the United States have lowered definition of hypertension by defining normal as systolic/diastolic BP <120/80 mm Hg; elevated BP as systolic between 120 and 129 mm Hg and diastolic <80 mm Hg; and stage 1 hypertension as systolic between 130 and 139 mm Hg or diastolic between 80 and 89 mm Hg. METHODS AND

resultsWe investigated the association between the new hypertension definition and cardiovascular disease mortality among Chinese in Singapore. We used data from 30 636 participants of a population-based cohort, the SCHS (Singapore Chinese Health Study), who had BPs measured using a standard protocol at ages 46 to 85 years between 1994 and 2005. Information on lifestyle factors was collected at recruitment (1993-1998) and follow-up 1 interviews (1999 and 2004). Mortality was identified via nationwide registry linkage up to December 31, 2016. Neither elevated BP (hazard ratio, 0.89; 95% confidence interval, 0.74-1.07) nor stage 1 hypertension (hazard ratio, 0.94; 95% confidence interval, 0.81-1.11) was associated with increased risk of cardiovascular mortality compared with normal BP in the whole cohort. Stage 1 hypertension was associated with increased cardiovascular risk only in those <65 years of age and without a history of cardiovascular disease (hazard ratio, 1.40; 95% confidence interval, 1.01-1.94), but not in those ≥65 years of age or with a history of cardiovascular disease.

conclusionsOur data suggest that the newly defined stage 1 hypertension may not be associated with increased cardiovascular mortality across all ages among Chinese in Singapore, but that the at-risk subpopulation is limited to those <65 years of age and without a prior cardiovascular disease.

Indexed as

AgedBlood PressureBlood Pressure DeterminationCardiovascular DiseasesCause of DeathDiastoleExerciseFemaleHumansHypertensionMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsSingaporecardiovascular diseaseChinesehigh blood pressuremortalityprehypertension

Identifiers

PMID29636346
PMCPMC6015396
OpenAlexW2797444644

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.