Evidence map›Paper›PMID 29636118›Full record

ReviewPublic health nutrition2018

Replacement of saturated and trans-fatty acids in the diet v. CVD risk in the light of the most recent studies.

Magdalena Makarewicz-Wujec, Anna Dworakowska, Małgorzata Kozłowska-Wojciechowska

Open access · bronzeAbstract readReview
In one paragraph

Review in Public health nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Magdalena Makarewicz-WujecDepartment of Clinical Pharmacy and Pharmaceutical Care,Medical University of Warsaw,Banacha 1,02-097 Warsaw,Poland.
Anna DworakowskaDepartment of Clinical Pharmacy and Pharmaceutical Care,Medical University of Warsaw,Banacha 1,02-097 Warsaw,Poland.
Małgorzata Kozłowska-WojciechowskaDepartment of Clinical Pharmacy and Pharmaceutical Care,Medical University of Warsaw,Banacha 1,02-097 Warsaw,Poland.
Medical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo present and discuss results of the most recent studies pertaining to the effects of consumption of different types of fatty acids on the risk of CVD. The aim was also an attempt to answer the question of whether a revision of the current recommendations is necessary.

designA review of prospective cohort studies, systematic reviews and meta-analyses published in 2014-2017 on the effects of SFA and trans-fatty acid (TFA) intakes as well as various models of their replacement in the diet on CVD risk.

resultsResults of the new large prospective cohort studies pertaining to the effect of SFA consumption on CVD risk are contradictory. Similarly, the recent meta-analyses of clinical trials related to the effects of SFA substitution on CVD risk provided extremely different results, which is related to the application of different inclusion and exclusion criteria. Differences in results of randomised controlled trials may be caused by different methodologies of dietary parameter changes, varying duration of studies, as well as the time at which they were carried out.

conclusionsIt is extremely difficult to extrapolate results of recent studies to contemporary recommendations. It seems that there is a need for properly randomised studies on large groups, with good control of dietary and non-dietary parameters, which account for not only the sum of SFA and TFA, but also their source. Only such studies will allow for full evaluation of an effect of substituting SFA and TFA on cardiovascular risk.

Indexed as

Fatty AcidsTrans Fatty AcidsCardiovascular DiseasesDietHumansRisk FactorsFatty AcidsTrans Fatty AcidsCVD riskSFATrans-fatty acidsUnsaturated fatty acids

Identifiers

PMID29636118
PMCPMC11106013
OpenAlexW2799342202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.