Evidence map›Paper›PMID 29636115›Full record

ArticleGenome biology2018

A unique epigenomic landscape defines the characteristics and differentiation potentials of glioma stem cells.

Bing Yao, Peng Jin

Abstract readComment
In one paragraph

Article in Genome biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Bing YaoDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, 30322, USA. bing.yao@emory.edu.
Peng JinDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, 30322, USA. peng.jin@emory.edu.

Funding

Molecular Basis of rCGG-Mediated NeurodegenerationR01NS051630 · NINDS · EMORY UNIVERSITY · PI NELSON, DAVID LOREN · 2006 to 2023
$9.8M
Translational models of neurodevelopmental epigenetics and disease using human iPSCsP01NS097206 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SONG, HONGJUN · 2016 to 2020
$4.3M
Genome-wide Profiling of Brain DNA Hydroxymethylome in Alzheimer’s DiseaseRF1AG052476 · NIA · UNIVERSITY OF FLORIDA · PI BENNETT, DAVID ALAN, JIN, PENG · 2016 to 2019
$4.1M
Tet-mediated Epigenetic Modulation in AutismR01MH102690 · NIMH · EMORY UNIVERSITY · PI JIN, PENG, WARREN, STEPHEN T. · 2014 to 2017
$2.6M
5-Hydroxymethylcytosine in NeurodevelopmentR01NS079625 · NINDS · EMORY UNIVERSITY · PI JIN, PENG · 2012 to 2016
$1.7M
Foundation for the National Institutes of Health AG052476Foundation for the National Institutes of Health MH102690Foundation for the National Institutes of Health NS051630Foundation for the National Institutes of Health NS079625Foundation for the National Institutes of Health NS097206NIA NIH HHS RF1 AG052476NIMH NIH HHS R01 MH102690NINDS NIH HHS P01 NS097206NINDS NIH HHS R01 NS051630NINDS NIH HHS R01 NS079625
6 · The paper itself

Abstract

A new study reveals comprehensive and unique epigenetic properties of glioma stem cells, leading to novel molecular insights and therapeutic potentials toward glioblastoma multiforme treatment.

Indexed as

Brain NeoplasmsGlioblastomaCell DifferentiationCuesEpigenomicsHumansNeoplastic Stem Cells

Identifiers

PMID29636115
PMCPMC5894242

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.