ReviewHuman genomics2018
The development of large-scale de-identified biomedical databases in the age of genomics-principles and challenges.
Review in Human genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The ethical and legal landscape of brain data governance.PloS one · 2022Pooled it
- Characterizing core outcomes of responsible stewardship for human genomic data in the cloud.BMC medical genomics · 2026Article
- Ethical and regulatory requirements for conducting researcher-driven large-scale multinational genetic haematological studies: the INHERENT experience.Health research policy and systems · 2025Article
- Public Involvement and Engagement in Big Data Research: Scoping Review.Journal of participatory medicine · 2024Article
- New approaches in developing medicinal herbs databases.Database : the journal of biological databases and curation · 2023Review
- A leap of faith: building the trust in human biobanks.Frontiers in genetics · 2023Article
- Profit versus Quality: The Enigma of Scientific Wellness.Journal of personalized medicine · 2022Review
- Why Is the Electronic Health Record So Challenging for Research and Clinical Care?Methods of information in medicine · 2021Article
- Named Data Networking for Genomics Data Management and Integrated Workflows.Frontiers in big data · 2021Article
- Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier.British journal of cancer · 2020Article
- Integrated multi-omics approaches to improve classification of chronic kidney disease.Nature reviews. Nephrology · 2020Review
- The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research Database.Patterns (New York, N.Y.) · 2020Article
- Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: UsingComputational and structural biotechnology journal · 2020Article
- Dynamic-informed consent: A potential solution for ethical dilemmas in population sequencing initiatives.Computational and structural biotechnology journal · 2020Review
- Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity.Pharmacology & therapeutics · 2019Review
- Privacy-Preserving Analysis of Distributed Biomedical Data: Designing Efficient and Secure Multiparty Computations Using Distributed Statistical Learning Theory.JMIR medical informatics · 2019Article
- Informed Consent in Biomedical Research.Computational and structural biotechnology journal · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Contemporary biomedical databases include a wide range of information types from various observational and instrumental sources. Among the most important features that unite biomedical databases across the field are high volume of information and high potential to cause damage through data corruption, loss of performance, and loss of patient privacy. Thus, issues of data governance and privacy protection are essential for the construction of data depositories for biomedical research and healthcare. In this paper, we discuss various challenges of data governance in the context of population genome projects. The various challenges along with best practices and current research efforts are discussed through the steps of data collection, storage, sharing, analysis, and knowledge dissemination.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.