ArticleInternational health2018
Impact of mass drug administration campaigns depends on interaction with seasonal human movement.
Article in International health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Agent-based models of malaria transmission: a systematic review.Malaria journal · 2018Pooled it
- Impact of Community-Based Mass Testing and Treatment on Malaria Infection Prevalence in a High-Transmission Area of Western Kenya: A Cluster Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Trial
- Diagnostic performance of an ultra-sensitive RDT and a conventional RDT in malaria mass testing, treatment and tracking interventions in southern Ghana.Parasites & vectors · 2024Article
- Mass Drug Administration: Contextual Factor Considerations.The American journal of tropical medicine and hygiene · 2024Review
- Perennial malaria chemoprevention with and without malaria vaccination to reduce malaria burden in young children: a modelling analysis.Malaria journal · 2023Article
- A multiphase program for malaria elimination in southern Mozambique (the Magude project): A before-after study.PLoS medicine · 2020Observational
- Resurgence of malaria infection after mass treatment: a simulation study.Malaria journal · 2019Article
- Reducing malaria burden and accelerating elimination with long-lasting systemic insecticides: a modelling study of three potential use cases.Malaria journal · 2019Article
- Implementing population-based mass drug administration for malaria: experience from a high transmission setting in North Eastern Uganda.Malaria journal · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Mass drug administration (MDA) is a control and elimination tool for treating infectious diseases. For malaria, it is widely accepted that conducting MDA during the dry season results in the best outcomes. However, seasonal movement of populations into and out of MDA target areas is common in many places and could potentially fundamentally limit the ability of MDA campaigns to achieve elimination. Methods: A mathematical model was used to simulate malaria transmission in two villages connected to a high-risk area into and out of which 10% of villagers traveled seasonally. MDA was given only in the villages. Prevalence reduction under various possible timings of MDA and seasonal travel was predicted. Results: MDA is most successful when distributed outside the traveling season and during the village low-transmission season. MDA is least successful when distributed during the traveling season and when traveling overlaps with the peak transmission season in the high-risk area. Mistiming MDA relative to seasonal travel resulted in much poorer outcomes than mistiming MDA relative to the peak transmission season within the villages. Conclusions: Seasonal movement patterns of high-risk groups should be taken into consideration when selecting the optimum timing of MDA campaigns.
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Registered trials
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