Evidence map›Paper›PMID 29635402›Full record

Trial reportTranslational behavioral medicine2019

Effect of intensive diet and exercise on self-efficacy in overweight and obese adults with knee osteoarthritis: The IDEA randomized clinical trial.

Shannon L Mihalko, Phillip Cox, Daniel P Beavers, Gary D Miller, Barbara J Nicklas, Mary Lyles, David J Hunter, Felix Eckstein, Ali Guermazi, Richard F Loeser and 2 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Translational behavioral medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Effect of exercise training on psychological outcomes in adults with overweight or obesity: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
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  19. The burden of OA-health services and economics.Osteoarthritis and cartilage · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Shannon L MihalkoDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.
Phillip CoxDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.
Daniel P BeaversDepartment of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Gary D MillerDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.
Barbara J NicklasDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.
Mary LylesSection on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
David J HunterRheumatology Department, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia.
Felix EcksteinInstitute of Anatomy, Paracelsus Medical University, Salzburg, Austria.
Ali GuermaziDepartment of Radiology, Boston University School of Medicine, Boston, MA, USA.
Richard F LoeserThurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Paul DeVitaDepartment of Kinesiology, East Carolina University, Greenville, NC, USA.
Stephen P MessierDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.
Wake Forest University · USBoston University · USEast Carolina University · USParacelsus Medical University · ATUniversity of North Carolina at Chapel Hill · USUniversity of Sydney · AU

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
WORKER PROTECTION AGAINST AIRBORNE INFLUENZA - A PILOT STUDYM01RR007122 · NCRR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 1992 to 2010
$35.2M
Intensive Dietary Restriction with Exercise in ArthritisR01AR052528 · NIAMS · WAKE FOREST UNIVERSITY · PI MESSIER, STEPHEN P · 2006 to 2010
$2.9M
NCRR NIH HHS M01 RR007122NIAMS NIH HHS R01 AR052528NIA NIH HHS P30 AG021332
6 · The paper itself

Abstract

Physical activity decreases the risk of osteoarthritis (OA)-related disability; however, pain and lack of confidence represent barriers for older adults with knee OA. The purpose of this study was to examine (a) the baseline associations among self-efficacy and physical activity, function, and pain; (b) longitudinal changes in self-efficacy; and (c) whether self-efficacy mediates treatment effects on clinical outcomes. The Intensive Diet and Exercise for Arthritis (IDEA) trial was a single-blind, randomized controlled 18-month study including 454 overweight/obese older adults (M age = 66 years) with knee OA. Participants were randomized to one of three interventions: exercise (E), diet-induced weight loss (D), or both (D+E). Self-efficacy for gait, balance, and walking duration were assessed at baseline, 6 months, and 18 months. Baseline associations were tested using Pearson correlations, and group least squares means were compared using mixed linear models at follow-up. Participants with higher self-efficacy reported significantly better physical function and less knee pain at baseline, walked farther (6-min walk), and were more physically active (all |r| > 0.12, all p < .01). Significant differences between groups were detected for all self-efficacy measures at 18 months; the D+E group reported significantly (all p < .005) higher self-efficacy for gait, walking duration, and balance compared with the D- or E-only groups. Self-efficacy significantly (p < .05) mediated treatment effects on physical function and pain at 18 months. A combined intervention of diet-induced weight loss and exercise is the treatment of choice to maximize self-efficacy, improve physical function, and reduce pain in overweight/obese adults with knee OA.

Indexed as

Diet, ReducingExercise TherapyAgedArthralgiaCombined Modality TherapyExerciseExercise TestFemaleFollow-Up StudiesHumansMaleOsteoarthritis, KneeOverweightPostural BalanceSelf EfficacyTreatment OutcomeExerciseKnee osteoarthritisPhysical activitySelf-efficacyWeight loss

Identifiers

PMID29635402
PMCPMC6417150
OpenAlexW2795584597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.