ArticleJAMA2018
The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States.
Article in JAMA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 779 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Implementation of High Definition Screening Using Handheld Imaging and Digital Health Technologies Within a Learning Health System to Identify Cardiovascular Disease at the Point-of-care: The ASE-INNOVATE Program
Expanding Our Cancer Prevention and Control Infrastructure to Reduce Cancer and Other Chronic Disease Health Disparities in the Deep South
An Interprofessional-led Model of Care to Prevent and Treat Chronic Diseases Using a Whole Food, Plant-based Nutrition Program in a Primary Care Setting
Efficacy of Monopolar Dielectric Diathermy and Therapeutic Exercise on Pain, Functionality, Movement Phobia and Quality of Life in Patients With Chronic Neck Pain.
Addressing Food-Insecurity: Plant-Based Food Prescription Program to Improve Health Food Access
Total Lumbar Disc Prosthesis and Subsequent Work Activity 5 Years After Total Lumbar Disc Replacement
A Longitudinal, Randomized-Controlled Experiment of Healthy Food Policies in Online Retail Settings
Who cites it
779 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Efficacy of interventions for posttraumatic stress disorder symptoms induced by traumatic medical events: a systematic review.Health psychology review · 2025Pooled it
- Dietary Approaches to Stop Hypertension (DASH) for the primary and secondary prevention of cardiovascular diseases.The Cochrane database of systematic reviews · 2025Pooled it
- Efficacy of Steroid Facet Joint Injections for Axial Spinal Pain and Post Radiofrequency Ablation Neuritis: A Systematic Review.Current pain and headache reports · 2025Pooled it
- Multi-ancestry meta-analysis of genome-wide association studies discovers 67 new loci associated with chronic back pain.Nature communications · 2025Pooled it
- Health-promotion interventions targeting multiple behaviors: A meta-analytic review of general and behavior-specific processes of change.Psychological bulletin · 2024Pooled it
- Does manual therapy meaningfully change quantitative sensory testing and patient reported outcome measures in patients with musculoskeletal impairments related to the spine?: A 'trustworthy' systematic review and meta-analysis.The Journal of manual & manipulative therapy · 2024Pooled it
- Unconditional cash transfers to improve health behaviors among primary care patients: a qualitative sub-study of a randomized clinical trial.Social science & medicine (1982) · 2026Trial
- Effectiveness of a digital weight management program on diet quality: a randomized controlled trial.The American journal of clinical nutrition · 2025Trial
- Barriers and facilitators to self-management in people with back-related leg pain: a qualitative secondary analysis.Chiropractic & manual therapies · 2025Trial
- Trial
- Effectiveness of Jingjin Therapy for Non-Specific Chronic Neck Pain with Extension Dysfunction: A Randomised Controlled Trial.Journal of pain research · 2025Trial
- Comparison of Sales From Vending Machines With 4 Different Food and Beverage Messages: A Randomized Trial.JAMA network open · 2024Trial
- Machine Learning Accurately Predicts Costs and Identifies Disparities for Common Outpatient Hand Surgeries.Journal of hand surgery global online · 2027Article
- Evaluation of a Digital Food and Nutrition Literacy Survey to Support Improvements in Diet Quality.Current developments in nutrition · 2026Article
- EBM BLS: Beta-blockers Fail to Improve Cardiovascular Outcomes in Patients with Myocardial Infarction and Preserved Ejection fraction.Journal of general internal medicine · 2026Article
- Physical Health Conditions Among Suicide Decedents: National Violent Death Reporting System, U.S., 2020-2023.American journal of preventive medicine · 2026Article
- Plant-based diets, stroke, and heart outcomes: a prospective study of the REasons for Geographic and Racial Differences in Stroke Cohort.The American journal of clinical nutrition · 2026Article
- Spatiotemporal Modeling of Premature Mortality in Mississippi: A County-Level Analysis of Years of Potential Life Lost, 2015-2025.Preventing chronic disease · 2026Article
- Examining stability of dietary patterns across time using repeated measures of dietary intake: Results from Black Women's Health Study.medRxiv : the preprint server for health sciences · 2026Article
- Impacts of incentivizing milk spending among SNAP participants.Health affairs scholar · 2026Article
719 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
116 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Several studies have measured health outcomes in the United States, but none have provided a comprehensive assessment of patterns of health by state. Objective: To use the results of the Global Burden of Disease Study (GBD) to report trends in the burden of diseases, injuries, and risk factors at the state level from 1990 to 2016. Design and Setting: A systematic analysis of published studies and available data sources estimates the burden of disease by age, sex, geography, and year. Main Outcomes and Measures: Prevalence, incidence, mortality, life expectancy, healthy life expectancy (HALE), years of life lost (YLLs) due to premature mortality, years lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 333 causes and 84 risk factors with 95% uncertainty intervals (UIs) were computed. Results: Between 1990 and 2016, overall death rates in the United States declined from 745.2 (95% UI, 740.6 to 749.8) per 100 000 persons to 578.0 (95% UI, 569.4 to 587.1) per 100 000 persons. The probability of death among adults aged 20 to 55 years declined in 31 states and Washington, DC from 1990 to 2016. In 2016, Hawaii had the highest life expectancy at birth (81.3 years) and Mississippi had the lowest (74.7 years), a 6.6-year difference. Minnesota had the highest HALE at birth (70.3 years), and West Virginia had the lowest (63.8 years), a 6.5-year difference. The leading causes of DALYs in the United States for 1990 and 2016 were ischemic heart disease and lung cancer, while the third leading cause in 1990 was low back pain, and the third leading cause in 2016 was chronic obstructive pulmonary disease. Opioid use disorders moved from the 11th leading cause of DALYs in 1990 to the 7th leading cause in 2016, representing a 74.5% (95% UI, 42.8% to 93.9%) change. In 2016, each of the following 6 risks individually accounted for more than 5% of risk-attributable DALYs: tobacco consumption, high body mass index (BMI), poor diet, alcohol and drug use, high fasting plasma glucose, and high blood pressure. Across all US states, the top risk factors in terms of attributable DALYs were due to 1 of the 3 following causes: tobacco consumption (32 states), high BMI (10 states), or alcohol and drug use (8 states). Conclusions and Relevance: There are wide differences in the burden of disease at the state level. Specific diseases and risk factors, such as drug use disorders, high BMI, poor diet, high fasting plasma glucose level, and alcohol use disorders are increasing and warrant increased attention. These data can be used to inform national health priorities for research, clinical care, and policy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.