Evidence map›Paper›PMID 29634752›Full record

SynthesisPloS one2018

The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis.

Yuan Song, Ya Liu, Yun Pan, Xiaofeng Yuan, Pengyu Chang, Yuan Tian, Weiwei Cui, Dong Li

Open access · goldAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yuan SongDepartment of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China.
Ya LiuDepartment of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China.
Yun PanTianqiao District of Ji'nan Food and Drug Administration, Ji'nan, Shandong Province, China.
Xiaofeng YuanDepartment of Pediatrics, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, China.
Pengyu ChangDepartment of Radiotherapy, The First Hospital of Jilin University, Changchun, China.
Yuan TianKey Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, College of Life Sciences, Jilin University, Changchun, China.
Weiwei CuiDepartment of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China.
Dong LiDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, China.ORCID 0000-0002-2508-3282
Jilin University · CNChangchun University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow birth weight infant (LBWIs) are prone to mental and behavioural problems. As an important constituent of the brain and retina, long chain polyunsaturated fatty acids are essential for foetal infant mental and visual development. The effect of lactation supplemented with long chain polyunsaturated fatty acids (LCPUFA) on the improvement of intelligence in low birth weight children requires further validation.

methodsIn this study, a comprehensive search of multiple databases was performed to identify studies focused the association between intelligence and long chain polyunsaturated fatty acid supplementation in LBWIs. Studies that compared the Bayley Scales of Infant Development (BSID) or the Wechsler Abbreviated Scale of Intelligence for Children (WISC) scores between LBWIs who were supplemented and controls that were not supplemented with LCPUFA during lactation were selected for inclusion in the meta-analysis.

resultsThe main outcome was the mean difference in the mental development index (MDI) and psychomotor development index (PDI) of the BSID and the full scale intelligence quotient (FSIQ), verbal intelligence quotient (VIQ) and performance intelligence quotient (PIQ) of the WISC between LBWIs and controls. Our findings indicated that the mean BSID or WISC scores in LBWIs did not differ between the supplemented groups and controls.

conclusionThis meta-analysis does not reveal that LCPUFA supplementation has a significant impact on the level of intelligence in LBWIs.

Indexed as

Dietary SupplementsLactationFatty Acids, UnsaturatedFemaleHumansInfantInfant, Low Birth WeightIntelligenceFatty Acids, Unsaturated

Identifiers

PMID29634752
PMCPMC5892917
OpenAlexW2797505409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.