Evidence map›Paper›PMID 29634445›Full record

ArticleJournal of women's health (2002)2018

The Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium: A Transdisciplinary Approach Toward Promoting Bladder Health and Preventing Lower Urinary Tract Symptoms in Women Across the Life Course.

Bernard L Harlow, Tamara G Bavendam, Mary H Palmer, Linda Brubaker, Kathryn L Burgio, Emily S Lukacz, Janis M Miller, Elizabeth R Mueller, Diane K Newman, Leslie M Rickey and 2 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of women's health (2002), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06798311 (Reducing Disparities in Urinary Control Symptoms for Minority Women), which is not on this map. Cited by 62 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 4 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06798311 narecruitingnot on this mapstarted 2024, after this paper: background citation

Reducing Disparities in Urinary Control Symptoms for Minority Women

TypeinterventionalSponsorUniversity of ChicagoRan2024 to 2027Enrolled80ConditionsUrinary Incontinence (UI), Lower Urinary Tract Symptoms (LUTS), Pelvic Floor DisorderArmsSUPPORT workbook
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 4 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Pooled it
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  13. Bladder Health Knowledge, Attitudes, and Beliefs among US Adolescent Women.Journal of pediatric and adolescent gynecology · 2025
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 12 institutions in 1 country.

Bernard L Harlow1 Department of Epidemiology, Boston University School of Public Health , Boston, Massachusetts.
Tamara G Bavendam2 Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , Bethesda, Maryland.
Mary H Palmer3 School of Nursing, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
Linda Brubaker4 Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Reproductive Medicine, University of California San Diego , San Diego, California.
Kathryn L Burgio5 Division of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham , Birmingham, Alabama.
Emily S Lukacz7 Division of Female Pelvic Medicine and Reconstructive Surgery, UC San Diego Health System , San Diego, California.
Janis M Miller8 School of Nursing, University of Michigan , Ann Arbor, Michigan.
Elizabeth R Mueller9 Division of Female Pelvic Medicine and Reconstructive Surgery, Stritch School of Medicine, Loyola-University of Chicago , Maywood, Illinois.
Diane K Newman10 Division of Urology, Department of Surgery, Perelman School of Medicine, University of Pennsylvania , Philadelphia, Pennsylvania.
Leslie M Rickey11 Department of Urology, Yale School of Medicine , New Haven, Connecticut.
Siobhan Sutcliffe12 Division of Public Health Sciences, Washington University School of Medicine , St. Louis, Missouri.
Denise Simons-Morton13 Morton Consulting , Bethesda, Maryland.
Boston University · USCalifornia University of Pennsylvania · USLoyola University Chicago · USMorpho (United States) · USNational Institutes of Health · USUC San Diego Health System · USUniversity of Alabama at Birmingham · USUniversity of California San Diego · USUniversity of Michigan · USUniversity of North Carolina at Chapel Hill · USWashington University in St. Louis · USYale University · US

Funding

Prevention of Lower Urinary Tract Symptoms in Women: Bladder Health Scientific and Data Coordinating Center (PLUS-SDCC) (U01)U01DK106786 · NIDDK · UNIVERSITY OF MINNESOTA · PI HARLOW, BERNARD L, RUDSER, KYLE · 2015 to 2019
$8.4M
University of Pennsylvania+ PLUS Clinical Center (PENN+PLUS CC)U01DK106892 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI NEWMAN, DIANE K., SMITH, ARIANA L · 2015 to 2024
$5.4M
PLUS Loyola Clinical CenterU01DK106898 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA, FITZGERALD, COLLEEN MARIE · 2015 to 2024
$4.7M
Prevention of LUTS: Bladder Health Clinical Center, UC San Diego SiteU01DK106827 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LACOURSIERE, DAPHNE YVETTE, LUKACZ, EMILY S. · 2015 to 2024
$4.5M
Pathways to LUTS Prevention: A Model for Public Education, Behavioral Skills, and Early DetectionU01DK106858 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MCGWIN, GERALD · 2015 to 2024
$4.5M
LUTS PREVENTION IN ADOLESCENT GIRLS AND WOMEN ACROSS THE LIFESPANU01DK106853 · NIDDK · WASHINGTON UNIVERSITY · PI SUTCLIFFE, SIOBHAN · 2015 to 2024
$4.0M
The Truly Healthy Bladder: Understanding Normal As A Pathway To Prevention Of Lower Urinary Tract Symptoms In WomenU01DK106893 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOW, LISA KANE · 2015 to 2024
$3.8M
Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium Yale Clinical Research CenterU01DK106908 · NIDDK · YALE UNIVERSITY · PI RICKEY, LESLIE M. · 2015 to 2024
$3.5M
NIDDK NIH HHS U01 DK106786NIDDK NIH HHS U01 DK106827NIDDK NIH HHS U01 DK106853NIDDK NIH HHS U01 DK106858NIDDK NIH HHS U01 DK106892NIDDK NIH HHS U01 DK106893NIDDK NIH HHS U01 DK106898NIDDK NIH HHS U01 DK106908
6 · The paper itself

Abstract

Lower urinary tract symptoms (LUTS) are highly prevalent in women, and are expected to impose a growing burden to individuals and society as the population ages. The predominance of research related to LUTS has focused on underlying pathology, disease mechanisms, or the efficacy of treatments for women with LUTS. Although this research has been vital for helping to reduce or ameliorate LUTS conditions, it has done little to prevent the onset of LUTS. Health promotion and prevention require an expansion of scientific inquiry beyond the traditional paradigm of studying disease mechanisms and treatment to the creation of an evidence base to support recommendations for bladder health promotion and, in turn, prevention of LUTS. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) introduced the concept of prevention as an important priority for women's urologic research as a prelude to supporting the formation of the Prevention of Lower Urinary Tract Symptoms (PLUS) research consortium. In this article, we introduce the PLUS research consortium to the scientific community; share the innovative paradigms by which the consortium operates; and describe its unique research mission: to identify factors that promote bladder health across the life course and prevent the onset of LUTS in girls and women.

Indexed as

ResearchWomen's HealthFemaleHealth PromotionHumansLower Urinary Tract SymptomsPrevalenceQuality of LifeUrinary Bladderbladderhealth promotionincontinencelower urinary tract symptomspreventionsocial ecologytransdisciplinaryurinary tract infectionurinationwomen's health

Identifiers

PMID29634445
PMCPMC5865253
OpenAlexW2754954886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.