ACE2 and pACE2: A Pair of Aces for Pulmonary Arterial Hypertension Treatment?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed.

1. A prospective study on endocrine function in patients with long-COVID symptoms.Hormones (Athens, Greece) · 2024
   Observational
2. ACE2 overexpression in corticotropin-releasing-hormone cells offers protection against pulmonary hypertension.Frontiers in neuroscience · 2023
   Article
3. Theoretical Investigation of the Coronavirus SARS-CoV-2 (COVID-19) Infection Mechanism and Selectivity.Molecules (Basel, Switzerland) · 2022
   Article
4. Review of registered clinical trials for the treatment of COVID-19.Drug development research · 2021
   Review
5. Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease.Gastroenterology · 2021
   Article
6. The role of extracellular vesicles in COVID-19 virus infection.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
   Review
7. Curcumin (a constituent of turmeric): New treatment option against COVID-19.Food science & nutrition · 2020
   Review
8. New understanding of the damage of SARS-CoV-2 infection outside the respiratory system.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
   Review
9. Reduced expression of COVID-19 host receptor,medRxiv : the preprint server for health sciences · 2020
   Article
10. Underlying Mechanisms and Candidate Drugs for COVID-19 Based on the Connectivity Map Database.Frontiers in genetics · 2020
    Article
11. Possible protective role of 17β-estradiol against COVID-19.Journal of allergy and infectious diseases · 2020
    Article
12. Pulmonary hypertension: Pathophysiology beyond the lung.Pharmacological research · 2020
    Review
13. COVID-19 and the pulmonary vascular injury.Journal of the renin-angiotensin-aldosterone system : JRAAS
    Article
14. The role and mechanism of AMPK in pulmonary hypertension.Therapeutic advances in respiratory disease
    Review

Corrections and comments

• Comment on
  AMP-activated Protein Kinase Phosphorylation of Angiotensin-Converting Enzyme 2 in Endothelium Mitigates Pulmonary Hypertension.2018

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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