Trial reportInternational journal of obesity (2005)2018
Effects of replacing diet beverages with water on weight loss and weight maintenance: 18-month follow-up, randomized clinical trial.
Trial report in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Artificially sweetened beverages do not influence metabolic risk factors: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- High versus low-added sugar consumption for the primary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2022Pooled it
- Effects of Unsweetened Preloads and Preloads Sweetened with Caloric or Low-/No-Calorie Sweeteners on Subsequent Energy Intakes: A Systematic Review and Meta-Analysis of Controlled Human Intervention Studies.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- The effects of low-calorie sweeteners on energy intake and body weight: a systematic review and meta-analyses of sustained intervention studies.International journal of obesity (2005) · 2021Pooled it
- Temporal Associations Among Body Mass Index, Fasting Insulin, and Systemic Inflammation: A Systematic Review and Meta-analysis.JAMA network open · 2021Pooled it
- Non-nutritive sweetened beverages versus water after a 52-week weight management programme: a randomised controlled trial.International journal of obesity (2005) · 2024Trial
- Artificial and Other Non-Nutritive Sweeteners, the Microbiome, and Cardiometabolic Health.Current atherosclerosis reports · 2026Review
- Low- or No-Energy Sweeteners and Body Weight Management: Dissecting a "Minor" Effect.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- Water intake, hydration, and weight management: the glass is half-full!Physiology & behavior · 2025Review
- The Effect of Non-Nutritive Sweeteners' Consumption on Body Weight: A Randomized-Controlled Trial.Food science & nutrition · 2025Article
- An Overview of Reviews on the Association of Low Calorie Sweetener Consumption With Body Weight and Adiposity.Advances in nutrition (Bethesda, Md.) · 2024Review
- Water for weight loss.Canadian family physician Medecin de famille canadien · 2022Article
- Drinking patterns and hydration biomarkers among young adults with different levels of habitual total drinking fluids intake in Baoding, Hebei Province, China: a cross-sectional study.BMC public health · 2020Article
- The amounts and contributions of total drinking fluids and water from food to total water intake of young adults in Baoding, China.European journal of nutrition · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBeneficial effects of replacing diet beverages (DBs) with water on weight loss, during a 24-week hypoenergetic diet were previously observed. However, it is not known whether this difference is sustained during a subsequent 12-month weight maintenance period.
objectiveTo evaluate effects of replacing DBs with water on body weight maintenance over a 12-month period in participants who undertook a 6-month weight loss plan.
designSeventy-one obese and overweight adult women (body mass index (BMI): 27-40 kg m
resultsA total of 71 participants who were randomly assigned were included in the study by using an intention-to-treat analysis. Greater additional weight loss (mean±s.d.) in the water group was observed compared with the DBs group after the 12-month follow-up period (-1.7±2.8 vs -0.1±2.7 kg, P=0.001). BMI decreased more in the water group than in the DBs group (-0.7±1 vs -0.05±1.1 kg m
conclusionsReplacement of DBs with water after the main meal in women who were regular users of DBs may cause further weight reduction during a 12-month weight maintenance program. It may also offer benefits in carbohydrate metabolism including improvement of insulin resistance over the long-term weight maintenance period.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.