Evidence map›Paper›PMID 29633968›Full record

ArticleActa crystallographica. Section F, Structural biology communications2018

Structural view of the helicase reveals that Zika virus uses a conserved mechanism for unwinding RNA.

Lei Li, Jin Wang, Zhihui Jia, Neil Shaw

Open access · bronzeAbstract read
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lei LiState Key Laboratory of Biotherapy and Cancer Center/National Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0003-4720-1339
Jin WangState Key Laboratory of Biotherapy and Cancer Center/National Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Zhihui JiaLaboratory of Structural Biology and MOE Laboratory of Protein Science, School of Medicine, Tsinghua University, Beijing 100084, People's Republic of China.
Neil ShawNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing 100101, People's Republic of China.
Sichuan University · CNInstitute of Biophysics · CNTsinghua University · CN

Funding

National Natural Science Foundation of China 31000332National Natural Science Foundation of China 31100208National Natural Science Foundation of China 31100877National Natural Science Foundation of China 31110103915National Natural Science Foundation of China 31170782
6 · The paper itself

Abstract

Recent studies suggest a link between infection by Zika virus (ZIKV) and the development of neurological complications. The lack of ZIKV-specific therapeutics has alarmed healthcare professionals worldwide. Here, crystal structures of apo and AMPPNP- and Mn

Indexed as

Adenosine TriphosphateAdenylyl ImidodiphosphateAmino Acid SequenceCrystallizationCrystallography, X-RayManganeseModels, MolecularProtein ConformationProtein DomainsRNA HelicasesRNA, ViralSequence HomologyViral Nonstructural ProteinsZika VirusAdenosine TriphosphateAdenylyl ImidodiphosphateManganeseRNA HelicasesRNA, ViralViral Nonstructural Proteinscrystal structurehelicaseligandsZika virus

Identifiers

PMID29633968
PMCPMC5894106
OpenAlexW2791009424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.