Evidence map›Paper›PMID 29633939›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2018

Renal artery anatomy assessed by quantitative analysis of selective renal angiography in 1,000 patients with hypertension.

Lucas Lauder, Sebastian Ewen, Abraham Rami Tzafriri, Elazer Reuven Edelman, Thomas Felix Lüscher, Peter J Blankenstijn, Oliver Dörr, Markus Schlaich, Faisal Sharif, Michiel Voskuil and 6 more

Open access · greenAbstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Assessment of a "main renal artery + branches" ablation strategy for catheter-based circumferential ultrasonic renal denervation.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Aberrant right renal perfusion from right internal mammary artery.Journal of vascular surgery cases and innovative techniques · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Renal denervation in the management of hypertension.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Article
  12. Article
  13. Histological examination of renal nerve distribution, density, and function in humans.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Article
  14. Technical aspects should also be fully considered in order to obtain better effectiveness of RDN.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. A drug-induced hypotensive challenge to verify catheter-based radiofrequency renal denervation in an obese hypertensive swine model.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 6 countries.

Lucas LauderKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Universität des Saarlandes, Homburg/Saar, Germany.
Sebastian Ewen
Abraham Rami Tzafriri
Elazer Reuven Edelman
Thomas Felix Lüscher
Peter J Blankenstijn
Oliver Dörr
Markus Schlaich
Faisal Sharif
Michiel Voskuil
Thomas Zeller
Christian Ukena
Bruno Scheller
Michael Böhm
Felix Mahfoud
Renal artery anatomy in hypertensive patients study collaborators
Universitätsklinikum des Saarlandes · DESaarland University · DEBrigham and Women's Hospital · USHarvard University · USImperial College London · GBRoyal Perth Hospital · AUUniversitäts-Herzzentrum Freiburg-Bad Krozingen · DEUniversity Hospital Galway · IEUniversity Medical Center Utrecht · NL

Funding

Vascular Drug Delivery - Supplement for EquipmentR01GM049039 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI EDELMAN, ELAZER R · 1994 to 2019
$8.9M
NIGMS NIH HHS R01 GM049039
6 · The paper itself

Abstract

aimsWith increasing attention to renovascular causes and targets for hypertension there arises a critical need for more detailed knowledge of renal arterial anatomy. However, a standardised nomenclature is lacking. The present study sought to develop a standardised nomenclature for renal anatomy considering the complexity and variation of the renal arterial tree and to assess the applicability of the nomenclature. METHODS AND

resultsOne thousand hypertensive patients underwent invasive selective renal artery angiography in nine centres. Further, renovasography was performed in 249 healthy swine as a surrogate for normotensive anatomy. Anatomical parameters were assessed by quantitative vascular analysis. Patients' mean blood pressure was 168/90±26/17 mmHg. The right main renal artery was longer than the left (41±15 mm vs. 35±13 mm, p<0.001), but the left had a greater diameter (5.4±1.2 vs. 5.2±1.2 mm, p<0.001). Accessory renal arteries and renal artery disease were documented in 22% and 9% of the patients, respectively. Other than exhibiting a longer left main renal artery in uncontrolled hypertensives (+2.7 mm, p=0.034) there was no anatomical difference between patients with controlled and uncontrolled hypertension. Main renal artery mean diameter was smaller in patients with impaired kidney function (GFR <90 ml/min, left -0.5 mm, right -0.4 mm, both p<0.001).

conclusionsRenal arterial anatomy differs between sides but shows no difference between patients with and without blood pressure control. Impaired GFR was associated with small main renal artery diameter.

Indexed as

AdultAgedAged, 80 and overAnimalsArterial PressureBlood PressureBlood Pressure DeterminationFemaleHumansHypertensionKidneyMaleMiddle AgedRenal ArterySwine

Identifiers

PMID29633939
PMCPMC6541921
OpenAlexW2804932980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.