ArticleRenal failure2018
Diabetic retinopathy may predict the renal outcomes of patients with diabetic nephropathy.
Article in Renal failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 105 citations in OpenAlex.
- Establishment and validation of a prognostic nomogram for long-term low vision after diabetic vitrectomy.Frontiers in endocrinology · 2023Trial
- Literature-informed ensemble machine learning for three-year diabetic kidney disease risk prediction in type 2 diabetes: Development, validation, and deployment of the PSMMC NephraRisk model.Diabetes, obesity & metabolism · 2026Article
- Association of serum and vitreous homocysteine and uric acid concentrations with post-vitrectomy prognosis in patients with proliferative diabetic retinopathy.World journal of diabetes · 2026Article
- Clinical Model Predicting Presence of Diabetic Nephropathy in Renal Biopsy Performed on Patients with Diabetes.Journal of clinical medicine · 2026Article
- Assessment of TG/HDL-C and METS-IR as markers for diabetic retinopathy risk and severity in type 2 diabetes.Frontiers in medicine · 2026Article
- Diabetic retinopathy severity is associated with renal function deterioration in patients with diabetic kidney disease: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- How early can we detect diabetic retinopathy? A narrative review of imaging tools for structural assessment of the retina.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- Diabetic retinopathy and diabetic kidney disease, either isolated or associated, impact on the 10-year risk of cardiovascular disease: are we dealing with similar conditions?Archives of endocrinology and metabolism · 2025Article
- The influence of renal function on surgical outcomes of vitrectomy in patients with proliferative diabetic retinopathy.Frontiers in endocrinology · 2025Article
- Artificial Intelligence-Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy.Translational vision science & technology · 2024Article
- Article
- Factors related to type 2 diabetic retinopathy and their clinical application value.Frontiers in endocrinology · 2024Article
- Parallelism and non-parallelism in diabetic nephropathy and diabetic retinopathy.Frontiers in endocrinology · 2024Review
- Serum Globulin and Albumin-to-Globulin Ratio are Associated with Diabetic Kidney Disease but Not Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study.Journal of inflammation research · 2024Article
- Retinal microvascular changes in diabetic patients with diabetic nephropathy.BMC endocrine disorders · 2023Observational
- Diabetic Retinopathy and Dementia Association, Beyond Diabetes Severity.American journal of ophthalmology · 2023Article
- Association between Age at Type 2 Diabetes Onset and Diabetic Retinopathy: A Double-Center Retrospective Study.Journal of diabetes research · 2023Article
- Is preclinical diabetic retinopathy in diabetic nephropathy individuals more severe?Frontiers in endocrinology · 2023Article
- A bibliometric analysis of publications inRenal failure · 2023Review
- Correlation between diabetic retinopathy and diabetic nephropathy: a two-sample Mendelian randomization study.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe patients with Type 2 diabetes mellitus (T2DM) and diabetic retinopathy (DR) are prone to develop diabetic nephropathy (DN). In this study, we aimed to clarify the relationship between DR and the progression of DN in patients with T2DM.
methodsIn the cross-section study, 250 patients with T2DM and biopsy-proven DN were divided into two groups: 130 in the DN without DR group (DN group) and 120 in the DN + DR group. Logistic regression analysis was performed to identify risk factors for DR. Of the above 250 patients, 141 were recruited in the cohort study who received follow-up for at least 1 year and the influence of DR on renal outcome was assessed using Cox regression. Renal outcome was defined as the progression to end-stage renal disease (ESRD).
resultsIn the cross-section study, the severity of glomerular lesions (class IIb + III) and DM history >10 years were significantly associated with the odds of DR when adjusting for baseline proteinuria, hematuria, e-GFR, and interstitial inflammation. In the cohort study, a multivariate COX analysis demonstrated that the DR remained an independent risk factor for progression to ESRD when adjusting for important clinical variables and pathological findings (p < .05).
conclusionsThese findings indicated that the severity of glomerular lesions was significantly associated with DR and DR was an independent risk factor for the renal outcomes in patients with DN, which suggested that DR may predict the renal prognosis of patients with T2DM and DN.
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