ArticleActa bio-medica : Atenei Parmensis2018
Diabetic ketoacidosis at the onset of Type 1 diabetes in young children Is it time to launch a tailored campaign for DKA prevention in children <5 years?
Article in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Type 1 diabetes prediction in autoantibody-positive individuals: performance, time and money matter.Diabetologia · 2025Article
- Delayed diagnosis of new onset pediatric diabetes leading to diabetic ketoacidosis: a retrospective cohort study.Diagnosis (Berlin, Germany) · 2024Article
- Association between sitagliptin plus vitamin D3 (VIDPP-4i) use and clinical remission in patients with new-onset type 1 diabetes: a retrospective case-control study.Archives of endocrinology and metabolism · 2023Article
- A Clinical and Biochemical Comparative Study Of Diabetic Ketoacidosis (DKA) in Newly Diagnosed Vs Known Cases of Type 1 Diabetic Children.The review of diabetic studies : RDS · 2023Article
- Young Children with Type 1 Diabetes: Recent Advances in Behavioral Research.Current diabetes reports · 2022Review
- Epidemiologic Characteristics of Children with Diabetic Ketoacidosis Treated in a Pediatric Intensive Care Unit in a 10-Year-Period: Single Centre Experience in Croatia.Medicina (Kaunas, Lithuania) · 2022Article
- Increased Frequency of Diabetic Ketoacidosis: The Link With COVID-19 Pandemic.Frontiers in clinical diabetes and healthcare · 2022Article
- Pediatric Emergency Medicine Didactics and Simulation (PEMDAS): Pediatric Diabetic Ketoacidosis.MedEdPORTAL : the journal of teaching and learning resources · 2021Article
- A Multicenter Survey of Type I Diabetes Mellitus in Chinese Children.Frontiers in endocrinology · 2021Article
- A combined risk score enhances prediction of type 1 diabetes among susceptible children.Nature medicine · 2020Article
- Characteristics of Children with Diabetic Ketoacidosis Treated in Pediatric Intensive Care Unit: Two-Center Cross-Sectional Study in Croatia.Medicina (Kaunas, Lithuania) · 2019Article
- Impact of Early Diabetic Ketoacidosis on the Developing Brain.Diabetes care · 2019Observational
- Diabetic Ketoacidosis at Onset of Type 1 Diabetes: Rates and Risk Factors Today to 15 Years Ago.Global pediatric health · 2019Article
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11 authors.
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Abstract
aimTo analyze clinical characteristics associated with the occurrence of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes (T1D) in children aged <5 years in order to identify early signs or symptoms useful to prevent DKA appearance.
methodsData of patients with newly diagnosed TID aged <5 years (Group 1) and 6-10 years old (Group 2) coming from the province of Parma were collected in the period 2012-2016.
resultsMild/moderate ketoacidosis at diabetes diagnosis occurred more frequently in Group 1 than in Group 2 patients (p<0.0015). Severe DKA incidence was higher in children below 5 (21.8%) than in those over 5 years of age (3.75%; p=0.021). Latent period before overt T1D diagnosis was longer in Group 1 than in Group 2 patients (p=0.0081). During this latent period similar indicators were recorded among parents of children <3 years old: frequent use of disposable baby diapers (87%), wet baby diapers because of a large amount of urine (86%), body weight loss (79%). In children aged 3-4 years reported symptoms consisted of polyuria (89%), polydipsia (79%), fatigue (72%). In Group 2 patients predominant signs concern unusual episodes of enuresis.
conclusionsWe believe that it is time to launch a DKA prevention campaign tailored for children under 5 years old and focused just on the above-mentioned three warning signs. Information program must involves pediatricians, pediatric nurses, new moms and nursery school teachers.
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