Evidence map›Paper›PMID 29633730›Full record

ArticleActa bio-medica : Atenei Parmensis2018

An uncommon case of chronic myeloid leukemia with variant cytogenetic.

Mohamed A Abdullah, Aliaa Amer, Zafar Nawaz, Ali S Abdullah, Ahmad Al-Sabbagh, Samah Kohla, Abdulqadir J Nashwan, Mohamed A Yassin

Abstract readCase Reports
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Dasatinib induced pleuro-pericardial effusion.Acta bio-medica : Atenei Parmensis · 2020
    Article
  3. Dasatinib induced pleural effusions - Reply.Acta bio-medica : Atenei Parmensis · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Mohamed A AbdullahDepartment of Medical Oncology, Hematology Section, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar. yassinmoha@gmail.com.
Aliaa AmerDepartment of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar. yassinmoha@gmail.com.
Zafar NawazDepartment of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar. yassinmoha@gmail.com.
Ali S AbdullahDepartment of Medical Education, Internal Medicine Section, Hamad Medical Corporation, Doha, Qatar. yassinmoha@gmail.com.
Ahmad Al-SabbaghDepartment of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar;. yassinmoha@gmail.com.
Samah KohlaClinical Pathology Department, Faculty of Medicine, AlAzhar University, Cairo, Egypt. yassinmoha@gmail.com.
Abdulqadir J NashwanDepartment of Medical Oncology, Hematology Section, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar. yassinmoha@gmail.com.
Mohamed A YassinDepartment of Medical Oncology, Hematology Section, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar. yassinmoha@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic Myeloid Leukemia (CML) is myeloproliferative neoplasm characterized by Philadelphia chromosome which is a balanced translocation between chromosome 9 and 22 in 90% of cases. However, variant cytogenetic still happens in 5-10 % of cases, the importance of which is controversial as well as its response to therapy, prognosis and progression to acute leukemias. Here we report a male patient with CML and variant cytogenetic who responded to low dose of Dasatinib (50 mg daily).

Indexed as

Abnormal KaryotypeTranslocation, GeneticAntineoplastic AgentsBone MarrowChromosome AberrationsChromosomes, Human, Pair 17Chromosomes, Human, Pair 22Chromosomes, Human, Pair 9DasatinibHumansIn Situ Hybridization, FluorescenceLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMaleMiddle AgedMolecular Targeted TherapyProtein Kinase InhibitorsAntineoplastic AgentsDasatinibProtein Kinase Inhibitors

Identifiers

PMID29633730
PMCPMC6179100

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.