Evidence map›Paper›PMID 29633693›Full record

ArticleFunctional neurology

Multicentre registry of brain-injured patients with disorder of consciousness: rationale and preliminary data.

A Pascarella, S Fiorenza, O Masotta, V Tibollo, D Vella, Anna Maria Nardone, Marta Rossi, P Volanti, F Madonia, Gaetano Cstronovo and 13 more

Abstract readMulticenter Study
In one paragraph

Article in Functional neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Predicting outcome in disorders of consciousness: A mega-analysis.Annals of clinical and translational neurology · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

A Pascarella
S Fiorenza
O Masotta
V Tibollo
D Vella
Anna Maria Nardone
Marta Rossi
P Volanti
F Madonia
Gaetano Cstronovo
D De Cicco
Caterina Guarnaschelli
M P Achilli
C Chiapparino
M T Angelillo
M A Tommasi
F Pisano
G Grioni
G Vezzadini
G Ferriero
S Salvaderi
R Bellazzi
Anna Estraneo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnostic accuracy and reliable estimation of clinical evolution are challenging issues in the management of patients with disorders of consciousness (DoC). Longitudinal systematic investigations conducted in large cohorts of patients with DoC could make it possible to identify reliable diagnostic and prognostic markers. On the basis of this consideration, we devised a multicentre prospective registry for patients with DoC admitted to ten intensive rehabilitation units. The registry collects homogeneous and detailed data on patients' demographic and clinical features, neurophysiological and neuroimaging findings, and medical and surgical complications. Here we present the rationale and the design of the registry and the preliminary results obtained in 53 patients with DoC (vegetative state or minimally conscious state) enrolled during the first seven months of the study. Data at 6-month post-injury follow-up were available for 46 of them. This registry could be an important tool for collecting high-quality data through the application of rigorous methods, and it could be used in the routine management of patients with DoC admitted to rehabilitation settings.

Indexed as

Neurological RehabilitationRegistriesAdolescentAdultAgedAged, 80 and overConsciousness DisordersElectroencephalographyFemaleFollow-Up StudiesHumansItalyMaleMiddle AgedOutcome Assessment, Health CareProspective Studies

Identifiers

PMID29633693
PMCPMC5901937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.