Evidence map›Paper›PMID 29633540›Full record

ArticleInternational forum of allergy & rhinology2018

Factor analysis of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis.

Jose L Mattos, Rodney J Schlosser, Adam S DeConde, Madison Hyer, Jess C Mace, Timothy L Smith, Zachary M Soler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International forum of allergy & rhinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
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  4. Observational
  5. Article
  6. Efficacy and safety of dupilumab in the treatment of CRSwNP in the real-life setting: a review of the literature.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Review
  7. Validity and Reliability of the Malay Questionnaire for Olfactory Disorders.The Malaysian journal of medical sciences : MJMS · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Predictive significance of the questionnaire of olfactory disorders-negative statements for olfactory loss in patients with chronic rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  13. Article
  14. Article
  15. What about using sniffin' sticks 12 items test to screen post-COVID-19 olfactory disorders?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jose L MattosDivision of Rhinology and Sinus Surgery, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC.ORCID 0000-0001-8766-1626
Rodney J SchlosserDivision of Rhinology and Sinus Surgery, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC.
Adam S DeCondeDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of California, San Diego, San Diego, CA.
Madison HyerDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
Jess C MaceDepartment of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, OR.
Timothy L SmithDepartment of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, OR.ORCID 0000-0002-6424-7083
Zachary M SolerDivision of Rhinology and Sinus Surgery, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC.

Funding

DETERMINANTS OF SURGICAL OUTCOMES IN CHRONIC SINUSITISR01DC005805 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SMITH, TIMOTHY L, SOLER, ZACHARY M · 2004 to 2020
$7.6M
Olfactory-specific inflammation and disease severity in chronic rhinosinusitisR03DC013651 · NIDCD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SOLER, ZACHARY M · 2013 to 2015
$449k
NIDCD NIH HHS R01 DC005805NIDCD NIH HHS R03 DC013651
6 · The paper itself

Abstract

backgroundOlfactory-specific quality of life (QOL) can be measured using the Questionnaire of Olfactory Disorders-Negative Statements (QOD-NS), which examines various aspects of olfactory dysfunction. It is unknown if certain factors of the QOD-NS differentially impact QOL.

methodsPatients with chronic rhinosinusitis (CRS) completed the QOD-NS, 22-item Sino-Nasal Outcome Test (SNOT-22), Medical Outcomes Study Short Form 6-D (SF-6D) health utility measure, and Patient Health Questionnaire-2 (PHQ-2) depression screen. Exploratory factor analysis of the QOD-NS was performed. Associations between QOD-NS factors and other QOL metrics were analyzed before and after endoscopic sinus surgery (ESS).

resultsOutcomes were examined on 132 patients. The QOD-NS contains 4 distinct factors. There was no difference in associations between the different factors and baseline clinical characteristics. ESS had greatest effect size (d) on factors 2 and 4 (d = 0.29 and 0.27, respectively, p < 0.05). Postsurgical changes in the SF-6D and SNOT-22 had the strongest correlation with factor 2 scores (r = 0.29 and 0.34, respectively, p < 0.05), and changes in the PHQ-2 had the strongest correlation to factor 3 (r = 0.24, p < 0.05). Abnormal QOD-NS scores at baseline were associated with effect size increases of 50% to 100% (p < 0.05).

conclusionThe QOD-NS measures 4 distinct factors. Eating-related questions had the greatest improvement after ESS. Health utility and CRS-specific QOL improvement most strongly associated with factor 2, while PHQ-2 changes are most highly associated with factor 3, suggesting a differential impact of the factors of the QOD-NS on varying aspects of QOL.

Indexed as

SmellSurveys and QuestionnairesAdultAgedChronic DiseaseEndoscopyFactor Analysis, StatisticalFemaleHumansMaleMiddle AgedOlfaction DisordersParanasal SinusesQuality of LifeRhinitisSinusitiseatingolfactionQODquality of lifesinusitistaste

Identifiers

PMID29633540
PMCPMC6035764

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.