Evidence map›Paper›PMID 29633393›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018

Towards the Prediction of Global Solution State Properties for Hydrogen Bonded, Self-Associating Amphiphiles.

Lisa J White, Stilyana N Tyuleva, Ben Wilson, Helena J Shepherd, Kendrick K L Ng, Simon J Holder, Ewan R Clark, Jennifer R Hiscock

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lisa J WhiteSchool of Physical Sciences, University of Kent, Canterbury, Kent, CT2 7NH, United Kingdom.
Stilyana N TyulevaSchool of Physical Sciences, University of Kent, Canterbury, Kent, CT2 7NH, United Kingdom.
Ben WilsonSchool of Physical Sciences, University of Kent, Canterbury, Kent, CT2 7NH, United Kingdom.
Helena J ShepherdSchool of Physical Sciences, University of Kent, Canterbury, Kent, CT2 7NH, United Kingdom.
Kendrick K L NgSchool of Physical Sciences, University of Kent, Canterbury, Kent, CT2 7NH, United Kingdom.
Simon J HolderSchool of Physical Sciences, University of Kent, Canterbury, Kent, CT2 7NH, United Kingdom.
Ewan R ClarkSchool of Physical Sciences, University of Kent, Canterbury, Kent, CT2 7NH, United Kingdom.
Jennifer R HiscockSchool of Physical Sciences, University of Kent, Canterbury, Kent, CT2 7NH, United Kingdom.ORCID http://orcid.org/0000-0002-1406-8802

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Through this extensive structure-property study we show that critical micelle concentration correlates with self-associative hydrogen bond complex formation constant, when combined with outputs from low level, widely accessible, computational models. Herein, we bring together a series of 39 structurally related molecules related by stepwise variation of a hydrogen bond donor-acceptor amphiphilic salt. The self-associative and corresponding global properties for this family of compounds have been studied in the gas, solid and solution states. Within the solution state, we have shown the type of self-associated structure present to be solvent dependent. In DMSO, this class of compound show a preference for hydrogen bonded dimer formation, however moving into aqueous solutions the same compounds are found to form larger self-associated aggregates. This observation has allowed us the unique opportunity to investigate and begin to predict self-association events at both the molecular and extended aggregate level.

Indexed as

aggregationhydrogen bondsmicellesself-assemblysupramolecular

Identifiers

PMID29633393
PMCPMC6055828

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.