Evidence map›Paper›PMID 29633297›Full record

ArticleMedical physics2018

Fluorescence-guided surgery and intervention - An AAPM emerging technology blue paper.

Brian W Pogue, Timothy C Zhu, Vasilis Ntziachristos, Keith D Paulsen, Brian C Wilson, Joshua Pfefer, Robert J Nordstrom, Maritoni Litorja, Heidrun Wabnitz, Yu Chen and 3 more

Abstract read
In one paragraph

Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Timothy C ZhuPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Vasilis NtziachristosInstitute of Biological and Medical Imaging, HelmholtzZentrum Munchen, Munich, Germany.
Keith D PaulsenThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Brian C WilsonDepartment of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Joshua PfeferUS Food and Drug Administration, Silver Spring, MD, USA.
Robert J NordstromNational Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Maritoni LitorjaNational Institute of Standards and Technology, Gaithersburg, MD, USA.
Heidrun WabnitzPhysikalisch-Technische Bundesanstalt, Berlin, Germany.
Yu ChenFischell Department of Bioengineering, University of Maryland, College Park, MD, USA.
Sylvain GiouxBeth Israel Deaconess Medical Center Harvard Medical School, Boston, MA, USA.
Bruce J TrombergBeckman Laser Institute, University of California Irvine, Irvine, CA, USA.
Arjun G YodhDepartment of Physics, University of Pennsylvania, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence-guided surgery (FGS) and other interventions are rapidly evolving as a class of technologically driven interventional approaches in which many surgical specialties visualize fluorescent molecular tracers or biomarkers through associated cameras or oculars to guide clinical decisions on pathological lesion detection and excision/ablation. The technology has been commercialized for some specific applications, but also presents technical challenges unique to optical imaging that could confound the utility of some interventional procedures where real-time decisions must be made. Accordingly, the AAPM has initiated the publication of this Blue Paper of The Emerging Technology Working Group (TETAWG) and the creation of a Task Group from the Therapy Physics Committee within the Treatment Delivery Subcommittee. In describing the relevant issues, this document outlines the key parameters, stakeholders, impacts, and outcomes of clinical FGS technology and its applications. The presentation is not intended to be conclusive, but rather to inform the field of medical physics and stimulate the discussions needed in the field with respect to a seemingly low-risk imaging technology that has high potential for significant therapeutic impact. This AAPM Task Group is working toward consensus around guidelines and standards for advancing the field safely and effectively.

Indexed as

ConsensusCurriculumHealth PersonnelHumansOptical ImagingPatient SafetyPractice Guidelines as TopicSocieties, MedicalSurgery, Computer-Assistedimagingimaging systeminterventionmolecularmolecular proberesection

Identifiers

PMID29633297
PMCPMC9560243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.