Evidence map›Paper›PMID 29633223›Full record

ArticleJournal of the American Society for Mass Spectrometry2018

Comprehensive Characterization of Swine Cardiac Troponin T Proteoforms by Top-Down Mass Spectrometry.

Ziqing Lin, Fang Guo, Zachery R Gregorich, Ruixiang Sun, Han Zhang, Yang Hu, Dhanansayan Shanmuganayagam, Ying Ge

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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  4. High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ziqing LinDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Fang GuoDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Zachery R GregorichDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Ruixiang SunDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Han ZhangDepartment of Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Yang HuDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Dhanansayan ShanmuganayagamDepartment of Animal Science, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Ying GeDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA. ge2@wisc.edu.
University of Wisconsin–Madison · USShandong Provincial Hospital · CN

Funding

Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3M
Training Program In Molecular AND Cellular PharmacologyT32GM008688 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI AUDHYA, ANJON · 1998 to 2020
$6.0M
Deciphering Myofilament Modifications in Ischemic CardiomyopathyR01HL109810 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2013 to 2024
$3.5M
Top Down Proteomics Of Myofilaments In Heart FailureR01HL096971 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2011 to 2021
$3.3M
Enabling Top-Down Proteomics through Materials Chemistry and NanotechnologyR01GM117058 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING, JIN, SONG · 2015 to 2023
$2.7M
Ultra High Resolution Mass Spectrometer for Biomedical ResearchS10OD018475 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2015 to 2015
$2.0M
NHLBI NIH HHS R01 HL096971NHLBI NIH HHS R01 HL109810NHLBI NIH HHS T32 HL007936NIGMS NIH HHS R01 GM117058NIGMS NIH HHS T32 GM008688NIGMS NIH HHS T32 GM008692NIH HHS GM117058NIH HHS HL096971NIH HHS HL109810NIH HHS OD018475NIH HHS S10 OD018475
6 · The paper itself

Abstract

Cardiac troponin T (cTnT) regulates the Ca

Indexed as

Amino Acid SequenceAnimalsChromatography, LiquidModels, MolecularPhosphorylationProtein ConformationProtein IsoformsProtein Processing, Post-TranslationalSequence Analysis, ProteinSwineTandem Mass SpectrometryTroponin TProtein IsoformsTroponin TCardiac troponinCollisionally activated dissociationElectron-capture dissociationElectron-transfer dissociationHeart diseaseProteoformTop-down proteomics

Identifiers

PMID29633223
PMCPMC6109964
OpenAlexW2796967793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.