Evidence map›Paper›PMID 29633004›Full record

ArticleEuropean radiology2018

Multiparametric MRI for Suspected Recurrent Prostate Cancer after HIFU:Is DCE still needed?

Raïssa Lotte, Alexandre Lafourcade, Pierre Mozer, Pierre Conort, Eric Barret, Eva Comperat, Malek Ezziane, Paul-Hugo Jouve de Guibert, Sebastian Tavolaro, Lisa Belin and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Abbreviated MR Protocols in Prostate MRI.Life (Basel, Switzerland) · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Raïssa LotteAcademic Department of Radiology, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France. raissalotte@hotmail.com.ORCID http://orcid.org/0000-0003-4056-0646
Alexandre LafourcadeAcademic Department of Statistic, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France.
Pierre MozerAcademic Department of Urology, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France.
Pierre ConortAcademic Department of Urology, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France.
Eric BarretUrology Department, Montsouris Institute, F-75014, Paris, France.
Eva ComperatAcademic Department of Pathology, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France.
Malek EzzianeAcademic Department of Radiology, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France.
Paul-Hugo Jouve de GuibertAcademic Department of Radiology, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France.
Sebastian TavolaroAcademic Department of Radiology, Hopital Tenon, AP-HP, Sorbonne University, Paris, France.
Lisa BelinAcademic Department of Statistic, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France.
Franck BoudgheneAcademic Department of Radiology, Hopital Tenon, AP-HP, Sorbonne University, Paris, France.
Olivier LucidarmeAcademic Department of Radiology, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France.
Raphaële Renard-PennaAcademic Department of Radiology, Hopital Pitié-Salpétrière, AP-HP, Sorbonne University, Paris, France. raphaele.renardpenna@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the added value of the dynamic contrast-enhanced sequence (DCE) to combination T2-weighted imaging (T2w) + diffusion-weighted imaging (DWI) in detecting prostate cancer (PCa) recurrence after HIFU (high-intensity focused ultrasound).

methodsForty-five males with clinical and biological suspected PCa recurrence were retrospectively selected. All underwent multi-parametric MRI (mpMRI) before biopsies. Two readers independently assigned a Likert score of cancer likelihood on T2w + DWI + DCE and T2w + DWI images. Prostatic biopsies were taken as the gold standard.

resultsRecurrent PCa was identified at biopsy for 37 patients (82%). Areas under the receiver-operating curve of T2w + DWI and T2w + DWI + DCE imaging were not significantly different for both readers. Using a Likert score ≥ 3 for the PCa diagnosis threshold, sensitivity at the lobe level for the (1) senior and (2) junior reader for T2w +DWI +DCE sensitivity was (1) 0.97 and (2) 0.94 vs. (1) 0.94 and (2) 0.97 for T2w + DWI.

conclusionAccuracy of mpMRI was not significantly improved by adding DCE to T2w + DWI. Sensitivity was high for T2w + DWI + DCE and T2w + DWI with no significant difference for either the junior or senior reader. KEY POINTS: • MpMRI has the capability to detect PCa recurrence in post-HIFU monitoring. • The sensitivity of T2w and DWI for detecting PCa recurrence was not improved by DCE. • Readers with different degrees of experience did not improve their performance with DCE.

Indexed as

Contrast MediaAgedBiopsyDiffusion Magnetic Resonance ImagingHigh-Intensity Focused Ultrasound AblationHumansImage EnhancementMagnetic Resonance ImagingMaleNeoplasm Recurrence, LocalProstateProstatic NeoplasmsRetrospective StudiesSensitivity and SpecificityContrast MediaContrast mediaDiffusion magnetic resonance imagingHigh-intensity focused ultrasound ablationNeoplasm recurrence, localProstate cancer

Identifiers

PMID29633004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.