ArticleEuropean radiology2018
Facial nerve tractography: A new tool for the detection of perineural spread in parotid cancers.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Advanced magnetic resonance neurography for preoperative facial nerve assessment and surgical planning in parotid tumors: a review of current evidence and surgical translation.Frontiers in oncology · 2026Review
- Comparison of multiple tractography pipelines for corticospinal tract reconstruction applied to brain tumor patients.Neuroradiology · 2025Article
- Diagnostic Accuracy of Contrast-Enhanced MRI for Detection of Perineural Spread in Head and Neck Cancer: A Systematic Review and Meta-Analysis.Journal of neurological surgery. Part B, Skull base · 2024Article
- Comparing the Double-Echo Steady-State with Water Excitation and Constructive Interference in Steady-State Sequence Techniques for Identifying Extracranial Facial Nerve and Tumor Positions in Patients with Parotid Tumors.AJNR. American journal of neuroradiology · 2024Article
- Intra-parotid facial nerve path by MRI tractography: radio-clinical comparison in parotid tumors.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Observational
- Review
- Article
- Ingenuity using 3D-MRI fusion image in evaluation before and after microvascular decompression for hemifacial spasm.Surgical neurology international · 2022Article
- Squamous Cell Carcinoma with Clinical Perineural Invasion: Challenges and Review in Single Case Study.Journal of radiology case reports · 2021Article
- Magnetic resonance neurography of the head and neck: state of the art, anatomy, pathology and future perspectives.The British journal of radiology · 2021Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine whether facial nerve MR tractography is useful in detecting PeriNeural Spread in parotid cancers.
methodsForty-five participants were enrolled. Thirty patients with surgically managed parotid tumors (15 malignant, 15 benign) were compared with 15 healthy volunteers. All of them had undergone 3T-MRI with diffusion acquisition and post-processing constrained spherical deconvolution-based tractography. Parameters of diffusion-weighted sequences were b-value 1,000 s/mm
resultsAverage pathlength was significantly higher in cases with PeriNeural Spread (39.86 mm [Quartile1: 36.27; Quartile3: 51.19]) versus cases without (16.23 mm [12.90; 24.90]), p<0.001. The threshold above which there was a significant association with PeriNeural Spread was set at 27.36 mm (Se: 100%; Sp: 84%; AUC: 0.96, 95% CI 0.904-1). There were no significant differences in FA between groups. Tractography map visual analyses directly displayed PeriNeural Spread in distal neural ramifications with sensitivity of 75%, versus 50% using morphological sequences.
conclusionsTractography could be used to identify facial nerve PeriNeural Spread by parotid cancers. KEY POINTS: • Tractography could detect facial nerve PeriNeural Spread in parotid cancers. • The average pathlength parameter is increased in case of PeriNeural Spread. • Tractography could map PeriNeural Spread more precisely than conventional imaging.
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