Evidence map›Paper›PMID 29632999›Full record

ArticleEuropean radiology2018

MR-based radiomics signature in differentiating ocular adnexal lymphoma from idiopathic orbital inflammation.

Jian Guo, Zhenyu Liu, Chen Shen, Zheng Li, Fei Yan, Jie Tian, Junfang Xian

Abstract read
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In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jian GuoDepartment of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1 of Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Zhenyu LiuCAS Key Laboratory of Molecular Imaging, Institute of Automation, Beijing, 100190, China.
Chen ShenSchool of Life Science and Technology, Xidian University, Xi'an, Shanxi, 710126, China.
Zheng LiDepartment of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1 of Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Fei YanDepartment of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1 of Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Jie TianCAS Key Laboratory of Molecular Imaging, Institute of Automation, Beijing, 100190, China. jie.tian@ia.ac.cn.
Junfang XianDepartment of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1 of Dongjiaominxiang, Dongcheng District, Beijing, 100730, China. cjr.xianjunfang@vip.163.com.ORCID http://orcid.org/0000-0003-2191-9393
Beijing Tongren Hospital · CNShandong Institute of Automation · CNXidian University · CN

Funding

Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support No. ZYLX201704High Level Health Technical Personnel of Bureau of Health in Beijing No. 2014-2-005Key Talent Project of Beijing No. 2014001The Priming Scientific Research Foundation for the Senior Researcher in Beijing Tongren Hospital, Capital Medical University 2016-YJJ-GGL-011
6 · The paper itself

Abstract

objectivesTo assess the value of the MR-based radiomics signature in differentiating ocular adnexal lymphoma (OAL) and idiopathic orbital inflammation (IOI).

methodsOne hundred fifty-seven patients with pathology-proven OAL (84 patients) and IOI (73 patients) were divided into primary and validation cohorts. Eight hundred six radiomics features were extracted from morphological MR images. The least absolute shrinkage and selection operator (LASSO) procedure and linear combination were used to select features and build radiomics signature for discriminating OAL from IOI. Discriminating performance was assessed by the area under the receiver-operating characteristic curve (AUC). The predictive results were compared with the assessment of radiologists by chi-square test.

resultsFive radiomics features were included in the radiomics signature, which differentiated OAL from IOI with an AUC of 0.74 and 0.73 in the primary and validation cohorts respectively. There was a significant difference between the classification results of the radiomics signature and those of a radiology resident (p < 0.05), although there was no significant difference between the results of the radiomics signature and those of a more experienced radiologist (p > 0.05).

conclusionsRadiomics features have the potential to differentiate OAL from IOI. KEY POINTS: • Clinical and imaging findings of OAL and IOI often overlap, which makes diagnosis difficult. • Radiomics features can potentially differentiate OAL from IOI non invasively. • The radiomics signature discriminates OAL from IOI at the same level as an experienced radiologist.

Indexed as

Magnetic Resonance ImagingAdultAgedDiagnosis, DifferentialFemaleHumansImage Processing, Computer-AssistedInflammationIntraocular LymphomaMaleMiddle AgedOrbital DiseasesPrognosisRetrospective StudiesROC CurveInflammationLymphomaMagnetic resonance imaging (MRI)Orbital neoplasmsRadiomics

Identifiers

PMID29632999
OpenAlexW2797383245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.