Evidence map›Paper›PMID 29632993›Full record

ReviewAbdominal radiology (New York)2018

Contrast-enhanced ultrasonography in interventional oncology.

Sriharsha Gummadi, John R Eisenbrey, Andrej Lyshchik

Open access · greenAbstract readReview
In one paragraph

Review in Abdominal radiology (New York), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sriharsha GummadiDepartment of Surgery, Lankenau Medical Center, Wynnewood, PA, USA.
John R EisenbreyDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
Andrej LyshchikDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA. Andrej.Lyshchik@jefferson.edu.ORCID 0000-0001-8930-2213
Thomas Jefferson University · US

Funding

2D and 3D Contrast-enhanced Ultrasound Evaluation of HCC ChemoembolizationR01CA194307 · NCI · THOMAS JEFFERSON UNIVERSITY · PI John Eisenbrey · 2016 to 2026
$5.3M
CONTRAST-ENHANCED ULTRASOUND EVALUATION OF FOCAL LIVER LESIONS IN PATIENTS WITH CIRRHOSIS OR OTHER RISK FACTORS FOR DEVELOPING HCCR01CA215520 · NCI · THOMAS JEFFERSON UNIVERSITY · PI LYSHCHIK, ANDREJ · 2017 to 2020
$2.4M
NCI NIH HHS R01 CA194307NCI NIH HHS R01 CA215520NIH HHS R01CA194307NIH HHS R01CA215520
6 · The paper itself

Abstract

Contrast-enhanced ultrasound (CEUS) has evolved from the use of agitated saline to second generation bioengineered microbubbles designed to withstand insonation with limited destruction. While only one of these newer agents is approved by the Food and Drug Administration for use outside echocardiography, interventional radiologists are increasingly finding off-label uses for ultrasound contrast agents. Notably, these agents have an extremely benign safety profile with no hepatic or renal toxicities and no radiation exposure. Alongside diagnostic applications, CEUS has begun to develop its own niche within the realm of interventional oncology. Certainly, the characterization of focal solid organ lesions (such as hepatic and renal lesions) by CEUS has been an important development. However, interventional oncologists are finding that the dynamic and real-time information afforded by CEUS can improve biopsy guidance, ablation therapy, and provide early evidence of tumor viability after locoregional therapy. Even more novel uses of CEUS include lymph node mapping and sentinel lymph node localization. Critical areas of research still exist. The purpose of this article is to provide a narrative review of the emerging roles of CEUS in interventional oncology.

Indexed as

Contrast MediaNeoplasmsUltrasonography, InterventionalHumansImage-Guided BiopsySentinel Lymph Node BiopsyContrast MediaContrast-enhanced ultrasoundInterventional oncologyInterventional radiology

Identifiers

PMID29632993
PMCPMC6276786
OpenAlexW2797186245

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.