Evidence map›Paper›PMID 29632814›Full record

ArticleFEBS open bio2018

The TNF-α-induced expression of miR-130b protects cervical cancer cells from the cytotoxicity of TNF-α.

Lei Yang, Yanli Wang, Shuainan Shi, Lili Xie, Tao Liu, Yuliang Wang, Hong Mu

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Diagnostic value for methylation in cervical cancer based on a small-molecule fluorescent probe targeting DNMT1.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. MicroRNA-130b functions as an oncogene and is a predictive marker of poor prognosis in lung adenocarcinoma.Laboratory investigation; a journal of technical methods and pathology · 2021
    Article
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lei YangDepartment of Clinical Laboratory Tianjin First Center Hospital China.
Yanli WangDepartment of Clinical Laboratory Tianjin Hospital of ITCWM Nankai Hospital China.
Shuainan ShiFirst Center Clinical College Tianjin Medical University China.
Lili XieDepartment of Clinical Laboratory Tianjin First Center Hospital China.
Tao LiuKey Laboratory for Critical Care Medicine of the Ministry of Health Tianjin China.
Yuliang WangDepartment of Clinical Laboratory Tianjin First Center Hospital China.
Hong MuDepartment of Clinical Laboratory Tianjin First Center Hospital China.
Tianjin Medical University · CNTianjin First Center Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumour necrosis factor alpha (TNF-α) is a multifunctional cytokine and has the capacity both to promote cell growth and to kill tumour cells by inducing cell apoptosis. However, many tumour cells develop resistance to the toxic effects of TNF-α. Thus, understanding the mechanism underlying the resistance of tumours to TNF-α toxicity and finding ways to overcome this resistance are urgently needed. In this study, we discovered that two cervical cancer cell lines, Hela and Siha, showed null responses to TNF-α cytotoxicity. However, in these cell lines, TNF-α stimulation promoted the expression of miR-130b and downregulated the expression of

Indexed as

cervical cancer cellmiR‐130bPTENTNF‐α resistance

Identifiers

PMID29632814
PMCPMC5881554
OpenAlexW2789842856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.