Evidence map›Paper›PMID 29632804›Full record

ArticleFEBS open bio2018

MicroRNA profiling during directed differentiation of cortical interneurons from human-induced pluripotent stem cells.

Jiajie Tu, Dandan Cao, Lu Li, Hoi-Hung Cheung, Wai-Yee Chan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS open bio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Species-Specific miRNAs in Human Brain Development and Disease.Frontiers in cellular neuroscience · 2019
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiajie TuMinistry of Education Key Laboratory for Regenerative Medicine (CUHK-Jinan University) School of Biomedical Sciences Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.ORCID 0000-0002-3895-3726
Dandan CaoMinistry of Education Key Laboratory for Regenerative Medicine (CUHK-Jinan University) School of Biomedical Sciences Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Lu LiCUHK-CAS Guangzhou Institute of Biomedicine and Health Joint Laboratory on Stem Cell and Regenerative Medicine School of Biomedical Sciences Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Hoi-Hung CheungMinistry of Education Key Laboratory for Regenerative Medicine (CUHK-Jinan University) School of Biomedical Sciences Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Wai-Yee ChanMinistry of Education Key Laboratory for Regenerative Medicine (CUHK-Jinan University) School of Biomedical Sciences Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induced pluripotent stem cells (iPSCs) are useful for modeling neuron development and related diseases. Cortical interneurons are essential players in neuropsychiatric diseases such as autism. miRNAs are a class of pivotal regulators in neural differentiation. Using a previously established model of cortical interneuron differentiation from human embryonic stem cells, we profiled miRNAs involved in differentiation from human iPSCs. A number of miRNAs were modulated in the differentiation process. This study captured the temporal

Indexed as

cortical interneuronshuman iPSCsmicroRNA

Identifiers

PMID29632804
PMCPMC5881541

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.