Evidence map›Paper›PMID 29632532›Full record

ArticleFrontiers in immunology2018

Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During

Ky V Hoang, Murugesan V S Rajaram, Heather Marie Curry, Mikhail A Gavrilin, Mark D Wewers, Larry S Schlesinger

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. The immune response toFrontiers in microbiology · 2025
    Review
  4. Article
  5. Neural-Cardiac Inflammasome Axis after Traumatic Brain Injury.Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ky V HoangCenter for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Murugesan V S RajaramCenter for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Heather Marie CurryCenter for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Mikhail A GavrilinDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine, Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, United States.
Mark D WewersDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine, Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, United States.
Larry S SchlesingerCenter for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
The Ohio State University · USInterface (United States) · USLung Institute · US

Funding

Vaccines and Therapies Against BotulismU54AI057153 · NIAID · UNIVERSITY OF CHICAGO · PI SHUMAN, HOWARD A · 2003 to 2013
$87.6M
Macrophage Inflammasome RegulationR01HL076278 · NHLBI · OHIO STATE UNIVERSITY · PI WEWERS, MARK DAMIAN · 2005 to 2019
$4.5M
NHLBI NIH HHS R01 HL076278NIAID NIH HHS U54 AI057153
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Caspase 1Cells, CulturedFrancisella tularensisHost-Pathogen InteractionsHumansImmune EvasionInflammasomesInterleukin-18Macrophage-1 AntigenMacrophagesMonocytesPhagocytosisras GTPase-Activating ProteinsSignal TransductionToll-Like Receptor 2Caspase 1InflammasomesInterleukin-18Macrophage-1 Antigenras GTPase-Activating ProteinsToll-Like Receptor 2caspase-1complement receptorFrancisellaimmune suppressioninflammasomeRas GTPase-activating protein

Identifiers

PMID29632532
PMCPMC5879101
OpenAlexW2792153360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.