ReviewFrontiers in neurology2018
Functional Assessment for Acute Stroke Trials: Properties, Analysis, and Application.
Review in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04235920 (Correlation of Alberta Stroke Program Early CT Score), which is not on this map. Cited by 28 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Correlation of Alberta Stroke Program Early CT Score (ASPECTS) With Cognitive Impairment and Outcome of Acute Ischemic Stroke
Who cites it
28 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence.Brain and behavior · 2025Pooled it
- Altered methylation pattern in EXOC4 is associated with stroke outcome: an epigenome-wide association study.Clinical epigenetics · 2022Pooled it
- Autologous bone-marrow mononuclear stem cell therapy in patients with stroke: a meta-analysis of comparative studies.Biomedical engineering online · 2020Pooled it
- UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Pooled it
- A systemic review of facial expression recognition (FER) in stroke: diagnosis and emerging applications in rehabilitation.Frontiers in neurologyPooled it
- Stem Cell-Based Therapies via Different Administration Route for Stroke: A Meta-analysis of Comparative Studies.Cell transplantationPooled it
- Efficacy and safety of cinepazide maleate injection in patients with acute ischemic stroke: a multicenter, randomized, double-blind, placebo-controlled trial.BMC neurology · 2020Trial
- Citicoline on the Barthel Index: Severe and moderate brain injury.Indian journal of pharmacologyTrial
- The stroke outcome optimization project: Acute ischemic strokes from a comprehensive stroke center.Scientific data · 2024Article
- Hi1a Improves Sensorimotor Deficit following Endothelin-1-Induced Stroke in Rats but Does Not Improve Functional Outcomes following Filament-Induced Stroke in Mice.ACS pharmacology & translational science · 2024Article
- Individualized goals expressed by patients undergoing stroke rehabilitation: an observational study.Journal of rehabilitation medicine · 2024Observational
- Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review.Brain sciences · 2024Review
- The relationship between social and psychological factors with cognitive impairment after stroke: a prospective study.Frontiers in psychiatry · 2024Article
- Apathy in subarachnoid hemorrhage: study protocol for a 1-year follow-up study.Frontiers in neurology · 2024Article
- Association Between Anemia and Clinical Outcome in Acute Ischemic Stroke Patients Treated With Endovascular Treatment.Journal of stroke · 2024Article
- Predicting institutionalization after Subacute Stroke Rehabilitation using the 12-Item World Health Organization Disability Assessment Schedule.Journal of rehabilitation medicine · 2023Observational
- Measurement Properties of the Patient-Specific Functional Scale in Rehabilitation for Patients With Stroke: A Prospective Observational Study.Physical therapy · 2023Observational
- Iron deficiency is related to low functional outcome in patients at early rehabilitation after acute stroke.Journal of cachexia, sarcopenia and muscle · 2022Observational
- Improving Visualization Methods of Utility-Weighted Disability Outcomes for Stroke Trials.Frontiers in neurology · 2022Article
- Domain-Specific Outcomes for Stroke Clinical Trials: What the Modified Rankin Isn't Ranking.Neurology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A measure of treatment effect is needed to assess the utility of any novel intervention in acute stroke. For a potentially disabling condition such as stroke, outcomes of interest should include some measure of functional recovery. There are many functional outcome assessments that can be used after stroke. In this narrative review, we discuss exemplars of assessments that describe impairment, activity, participation, and quality of life. We will consider the psychometric properties of assessment scales in the context of stroke trials, focusing on validity, reliability, responsiveness, and feasibility. We will consider approaches to the analysis of functional outcome measures, including novel statistical approaches. Finally, we will discuss how advances in audiovisual and information technology could further improve outcome assessment in trials.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.