Evidence map›Paper›PMID 29632427›Full record

ArticleWorld journal of gastroenterology2018

Fecal microbial dysbiosis in Chinese patients with inflammatory bowel disease.

Hai-Qin Ma, Ting-Ting Yu, Xiao-Jing Zhao, Yi Zhang, Hong-Jie Zhang

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

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  16. Graves Disease and Inflammatory Bowel Disease: A Bidirectional Mendelian Randomization.The Journal of clinical endocrinology and metabolism · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hai-Qin MaDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Ting-Ting YuDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Xiao-Jing ZhaoDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Yi ZhangDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Hong-Jie ZhangDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China. hjzhang06@163.com.
Jiangsu Province Hospital · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyze the alterations of fecal microbiota in Chinese patients with inflammatory bowel disease (IBD).

methodsFecal samples from 15 patients with Crohn's disease (CD) (11 active CD, 4 inactive CD), 14 patients with active ulcerative colitis (UC) and 13 healthy individuals were collected and subjected to 16S ribosomal DNA (rDNA) gene sequencing. The V4 hypervariable regions of 16S rDNA gene were amplified from all samples and sequenced by the Illumina MiSeq platform. Quality control and operational taxonomic units classification of reads were calculated with QIIME software. Alpha diversity and beta diversity were displayed with R software.

resultsCommunity richness (chao) and microbial structure in both CD and UC were significantly different from those in normal controls. At the phyla level, analysis of the microbial compositions revealed a significantly greater abundance of

conclusionOur study profiles specific characteristics and microbial dysbiosis in the gut of Chinese patients with IBD.

Indexed as

AdultBacteroidetesColitis, UlcerativeCrohn DiseaseDNA, RibosomalDysbiosisEscherichiaFecesFemaleGastrointestinal MicrobiomeHumansIntestinal MucosaMaleMiddle AgedProteobacteriaRNA, Ribosomal, 16SDNA, RibosomalRNA, Ribosomal, 16S16S ribosomal DNAChineseCrohn’s diseaseMicrobial dysbiosisUlcerative colitis

Identifiers

PMID29632427
PMCPMC5889826
OpenAlexW2795454040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.