ArticleJournal Of Elasticity2017
A Comparison of Phenomenologic Growth Laws for Myocardial Hypertrophy.
Article in Journal Of Elasticity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
- Multiscale model calibrated with a Bayesian algorithm predicts long-term outcomes of treatments for mitral valve regurgitation in animal models.Biomechanics and modeling in mechanobiology · 2026Article
- A modelling study of right ventricular growth with valvular regurgitation.Biomechanics and modeling in mechanobiology · 2026Article
- Computational model of coarctation of the aorta in rabbits suggests persistent ascending aortic remodeling post-correction.Biomechanics and modeling in mechanobiology · 2025Article
- Contributions of mechanical loading and hormonal changes to eccentric hypertrophy during volume overload: A Bayesian analysis using logic-based network models.PLoS computational biology · 2025Article
- Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease.Annals of biomedical engineering · 2024Article
- Guidelines for mechanistic modeling and analysis in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2024Review
- A homogenized constrained mixture model of cardiac growth and remodeling: analyzing mechanobiological stability and reversal.Biomechanics and modeling in mechanobiology · 2023Article
- The age of computational cardiology and future of long-term ablation target prediction for ventricular tachycardia.Frontiers in cardiovascular medicine · 2023Article
- Individual variability in animal-specific hemodynamic compensation following myocardial infarction.Journal of molecular and cellular cardiology · 2022Article
- Computational models of ventricular mechanics and adaptation in response to right-ventricular pressure overload.Frontiers in physiology · 2022Review
- Multiscale simulations of left ventricular growth and remodeling.Biophysical reviews · 2021Review
- Precision medicine in human heart modeling : Perspectives, challenges, and opportunities.Biomechanics and modeling in mechanobiology · 2021Review
- Computational models of cardiac hypertrophy.Progress in biophysics and molecular biology · 2021Review
- Biomechanics of infarcted left ventricle: a review of modelling.Biomedical engineering letters · 2020Review
- The role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodelling.Journal of cellular and molecular medicine · 2020Article
- Predictions of hypertrophy and its regression in response to pressure overload.Biomechanics and modeling in mechanobiology · 2020Article
- Computational modeling of cardiac growth and remodeling in pressure overloaded hearts-Linking microstructure to organ phenotype.Acta biomaterialia · 2020Review
- Evaluation of stimulus-effect relations in left ventricular growth using a simple multiscale model.Biomechanics and modeling in mechanobiology · 2020Article
- Propagation of uncertainty in the mechanical and biological response of growing tissues using multi-fidelity Gaussian process regression.Computer methods in applied mechanics and engineering · 2020Article
- Model of Anisotropic Reverse Cardiac Growth in Mechanical Dyssynchrony.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The heart grows in response to changes in hemodynamic loading during normal development and in response to valve disease, hypertension, and other pathologies. In general, a left ventricle subjected to increased afterload (pressure overloading) exhibits concentric growth characterized by thickening of individual myocytes and the heart wall, while one experiencing increased preload (volume overloading) exhibits eccentric growth characterized by lengthening of myocytes and dilation of the cavity. Predictive models of cardiac growth could be important tools in evaluating treatments, guiding clinical decision making, and designing novel therapies for a range of diseases. Thus, in the past 20 years there has been considerable effort to simulate growth within the left ventricle. While a number of published equations or systems of equations (often termed "growth laws") can capture some aspects of experimentally observed growth patterns, no direct comparisons of the various published models have been performed. Here we examine eight of these laws and compare them in a simple test-bed in which we imposed stretches measured during
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.