ArticleNature chemical biology2018
Ligand-receptor co-evolution shaped the jasmonate pathway in land plants.
Article in Nature chemical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
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Who cites it
102 citing papers in PubMed, 235 citations in OpenAlex.
- Hormone-metabolism crosstalk in plants: an integrated signaling network coordinating growth and stress adaptation.Plant signaling & behavior · 2026Review
- The cost of a meal: an ancestral plant strategy turns fatty acids into weapons against insect herbivores.The New phytologist · 2026Article
- Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026Review
- Weaponizing nutrition: plants use a double strategy to fight herbivory, converting nutritionally essential fatty acids into defensive oxylipin signals.The New phytologist · 2026Article
- Jasmonate Biosynthesis Across Bryophyte Lineages: Lessons fromPlants (Basel, Switzerland) · 2026Review
- Evolutionary shifts in plant adaptation mediated by phytohormones.Plant communications · 2026Review
- A multiplant transcriptomic atlas reveals conserved and lineage-specific defense architectures in response toProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Molecular insights into volatile organic compound sensing and signaling in plants.The Plant journal : for cell and molecular biology · 2026Review
- Evolution of molecular communication in the permanent Azolla symbiosis.The New phytologist · 2026Review
- Desiccation Tolerance in Moss and Liverwort: Insights into the Evolutionary Mechanisms of Terrestrialization.International journal of molecular sciences · 2026Review
- The plastid cysteine synthase complex regulates ABA biosynthesis and stomatal closure in Arabidopsis.Nature communications · 2025Article
- To immunity and beyond: the central role of jasmonate signalling in beneficial root-microbe-environment interactions.The New phytologist · 2025Review
- Transcriptomics and trans-organellar complementation reveal limited signaling of 12-cis-oxo-phytodienoic acid during early wound response in Arabidopsis.Nature communications · 2025Article
- Downstream metabolites of (+)-cis-12-oxo-phytodienoic acid function as noncanonical bioactive jasmonates in Arabidopsis thaliana.Nature communications · 2025Article
- Arabidopsis GH3.10 conjugates jasmonates.Plant biology (Stuttgart, Germany) · 2025Article
- Sexual reproduction in land plants: an evolutionary perspective.Plant reproduction · 2025Review
- Comparative transcriptomics in ferns reveals key innovations and divergent evolution of the secondary cell walls.Nature plants · 2025Article
- Article
- Accessible versatility underpins the deep evolution of plant specialized metabolism.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2025Review
- Amide conjugates of the jasmonate precursor cis-(+)-12-oxo-phytodienoic acid regulate its homeostasis during plant stress responses.Plant physiology · 2024Article
42 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phytohormone jasmonoyl-isoleucine (JA-Ile) regulates defense, growth and developmental responses in vascular plants. Bryophytes have conserved sequences for all JA-Ile signaling pathway components but lack JA-Ile. We show that, in spite of 450 million years of independent evolution, the JA-Ile receptor COI1 is functionally conserved between the bryophyte Marchantia polymorpha and the eudicot Arabidopsis thaliana but COI1 responds to different ligands in each species. We identified the ligand of Marchantia MpCOI1 as two isomeric forms of the JA-Ile precursor dinor-OPDA (dinor-cis-OPDA and dinor-iso-OPDA). We demonstrate that AtCOI1 functionally complements Mpcoi1 mutation and confers JA-Ile responsiveness and that a single-residue substitution in MpCOI1 is responsible for the evolutionary switch in ligand specificity. Our results identify the ancestral bioactive jasmonate and clarify its biosynthetic pathway, demonstrate the functional conservation of its signaling pathway, and show that JA-Ile and COI1 emergence in vascular plants required co-evolution of hormone biosynthetic complexity and receptor specificity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.