Evidence map›Paper›PMID 29632393›Full record

ArticleScientific reports2018

Coarse particulate matter (PM

Julia Y Ljubimova, Oliver Braubach, Rameshwar Patil, Antonella Chiechi, Jie Tang, Anna Galstyan, Ekaterina S Shatalova, Michael T Kleinman, Keith L Black, Eggehard Holler

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Impacts of Environmental Pollution on Brain Tumorigenesis.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Inflammatory effects of particulate matter air pollution.Environmental science and pollution research international · 2020
    Review
  18. Observational
  19. Neuropathology changed by 3- and 6-months low-level PMParticle and fibre toxicology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Julia Y LjubimovaDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, 90048, USA.
Oliver BraubachDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, 90048, USA. oliver.braubach@cshs.org.ORCID 0000-0003-2038-7954
Rameshwar PatilDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, 90048, USA.
Antonella ChiechiDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, 90048, USA.
Jie TangGenomics Core, Cedars-Sinai Medical Center, Los Angeles, 90048, USA.ORCID 0000-0002-3991-2539
Anna GalstyanDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, 90048, USA.
Ekaterina S ShatalovaDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, 90048, USA.
Michael T KleinmanDepartment of Community and Environmental Medicine Air Pollution Health Effects Laboratory, University of California, Irvine, 92697, USA.
Keith L BlackDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, 90048, USA.
Eggehard HollerDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, 90048, USA.
Cedars-Sinai Medical Center · USUniversity of California, Irvine · US

Funding

Nanoconjugate delivery of proliferation and checkpoint inhibitors to treat glial tumorsR01CA206220 · NCI · CEDARS-SINAI MEDICAL CENTER · PI LJUBIMOVA, JULIA Y · 2016 to 2020
$2.8M
Glial tumor image-guided surgery and treatmentR01CA209921 · NCI · TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION · PI HOLLER, EGGEHARD · 2016 to 2021
$2.6M
Differential MRI imaging for brain tumor metastases diagnosis and treatment monitoringR01CA188743 · NCI · CEDARS-SINAI MEDICAL CENTER · PI LJUBIMOVA, JULIA Y · 2015 to 2019
$2.5M
Nano immunoconjugates to treat primary and metastatic HER2 positive breast cancerR01CA230858 · NCI · CEDARS-SINAI MEDICAL CENTER · PI HOLLER, EGGEHARD, LJUBIMOVA, JULIA Y · 2019 to 2020
$1.3M
NCI NIH HHS R01 CA206220NCI NIH HHS R01 CA209921NCI NIH HHS R01 CA230858
6 · The paper itself

Abstract

Air pollution is linked to brain inflammation, which accelerates tumorigenesis and neurodegeneration. The molecular mechanisms that connect air pollution with brain pathology are largely unknown but seem to depend on the chemical composition of airborne particulate matter (PM). We sourced ambient PM from Riverside, California, and selectively exposed rats to coarse (PM

Indexed as

Air PollutantsAnimalsBiomarkers, TumorBrain ChemistryBrain NeoplasmsEncephalitisGene Expression ProfilingGene Expression RegulationLos AngelesNickelOrgan SpecificityParticle SizeParticulate MatterRatsSequence Analysis, RNASpectrophotometry, AtomicAir PollutantsBiomarkers, TumorNickelParticulate Matter

Identifiers

PMID29632393
PMCPMC5890281
OpenAlexW2797685495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.