ArticleNature communications2018
Stimulus dependent diversity and stereotypy in the output of an olfactory functional unit.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Rapid temporal processing in the olfactory bulb underlies concentration-invariant odor identification and signal decorrelation.Nature neuroscience · 2026Article
- The Periaqueductal Gray Selectively Supports Reversal Learning During a Flexible Discrimination Task in Mice.bioRxiv : the preprint server for biology · 2026Article
- Decoding olfactory bulb output: A behavioral assessment of rate, synchrony, and respiratory phase coding.iScience · 2025Article
- Essential Role of the Anterior Piriform Cortex in Mediating Social Novelty Output via a Top-Down Circuit.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Striatal and hippocampal contributions to instrumental learning in the mouse using high-resolution behavioral monitoring and fMRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- The primacy model and the structure of olfactory space.PLoS computational biology · 2024Article
- Fast-spiking interneuron detonation drives high-fidelity inhibition in the olfactory bulb.PLoS biology · 2024Article
- Fast-spiking interneuron detonation drives high-fidelity inhibition in the olfactory bulb.bioRxiv : the preprint server for biology · 2024Article
- Gain modulation and odor concentration invariance in early olfactory networks.PLoS computational biology · 2023Article
- Neuroscience: Seq-ing maps in the olfactory cortex.Current biology : CB · 2023Article
- The human odorant receptor OR10A6 is tuned to the pheromone of the commensal fruit flyiScience · 2022Article
- Article
- Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb.Nature communications · 2022Article
- Functional and multiscale 3D structural investigation of brain tissue through correlative in vivo physiology, synchrotron microtomography and volume electron microscopy.Nature communications · 2022Article
- Fluorescent protein transgenic mice for the study of CaFree radical biology & medicine · 2022Review
- Article
- Precise Holographic Manipulation of Olfactory Circuits Reveals Coding Features Determining Perceptual Detection.Neuron · 2020Article
- Antagonistic odor interactions in olfactory sensory neurons are widespread in freely breathing mice.Nature communications · 2020Article
- Manipulating synthetic optogenetic odors reveals the coding logic of olfactory perception.Science (New York, N.Y.) · 2020Article
- Discovering Precise Temporal Patterns in Large-Scale Neural Recordings through Robust and Interpretable Time Warping.Neuron · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Olfactory inputs are organized in an array of functional units (glomeruli), each relaying information from sensory neurons expressing a given odorant receptor to a small population of output neurons, mitral/tufted (MT) cells. MT cells respond heterogeneously to odorants, and how the responses encode stimulus features is unknown. We recorded in awake mice responses from "sister" MT cells that receive input from a functionally characterized, genetically identified glomerulus, corresponding to a specific receptor (M72). Despite receiving similar inputs, sister MT cells exhibit temporally diverse, concentration-dependent, excitatory and inhibitory responses to most M72 ligands. In contrast, the strongest known ligand for M72 elicits temporally stereotyped, early excitatory responses in sister MT cells, consistent across a range of concentrations. Our data suggest that information about ligand affinity is encoded in the collective stereotypy or diversity of activity among sister MT cells within a glomerular functional unit in a concentration-tolerant manner.
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