Evidence map›Paper›PMID 29632248›Full record

ReviewInfection and immunity2018

Are Sphingolipids and Serine Dipeptide Lipids Underestimated Virulence Factors of Porphyromonas gingivalis?

Ingar Olsen, Frank C Nichols

Open access · bronzeAbstract readReview
In one paragraph

Review in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Infection and immunity · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Lipidome of theBiochemistry · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. TLR2 Activation byFrontiers in immunology · 2022
    Article
  19. Novel Glycerophospholipid, Lipo- andMolecules (Basel, Switzerland) · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Ingar OlsenDepartment of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway.
Frank C NicholsDepartment of Oral Health and Diagnostic Sciences of the University of Connecticut School of Dental Medicine, Farmington, Connecticut, USA nichols@uchc.edu.
University of Connecticut · USUniversity of Oslo · NO

Funding

Porphyromonas gingivalis lipids mediate bone loss through TLR2R01DE021055 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI NICHOLS, FRANK C · 2011 to 2015
$1.9M
Porphyromonas gingivalis glycine lipids mediate bone loss through TLR2R01DE027642 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI NICHOLS, FRANK C · 2019 to 2022
$1.6M
Porphyromonas gingivalis lipids mediate bone loss through TLR2R56DE021055 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI NICHOLS, FRANK C · 2017 to 2017
$359k
NIDCR NIH HHS R01 DE021055NIDCR NIH HHS R01 DE027642NIDCR NIH HHS R56 DE021055
6 · The paper itself

Abstract

The keystone periodontal pathogen

Indexed as

Alveolar Bone LossCeramidesChronic PeriodontitisHumansLipopeptidesOsteoclastsPhosphorylationPorphyromonas gingivalisToll-Like Receptor 2Virulence FactorsCeramidesdihydroceramideLipopeptidesserine dipeptide lipid 654Toll-Like Receptor 2Virulence Factorsceramidesextraoral diseasesperiodontitisP. gingivalissphingolipidsvirulence factors

Identifiers

PMID29632248
PMCPMC6013676
OpenAlexW2797809402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.