Evidence map›Paper›PMID 29632243›Full record

ArticleEMBO reports2018

Disentangling the molecular determinants for Cenp-F localization to nuclear pores and kinetochores.

Alessandro Berto, Jinchao Yu, Stéphanie Morchoisne-Bolhy, Chiara Bertipaglia, Richard Vallee, Julien Dumont, Francoise Ochsenbein, Raphael Guerois, Valérie Doye

Open access · bronzeAbstract read
In one paragraph

Article in EMBO reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Kinetochore components are perinuclear and form condensates inbioRxiv : the preprint server for biology · 2025
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  16. Centromere Protein F (CENPF): A novel marker for salivary gland pathology.Journal of oral and maxillofacial pathology : JOMFP
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Alessandro BertoInstitut Jacques Monod, UMR7592, CNRS, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Jinchao YuInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris Sud, Université Paris-Saclay, Gif sur Yvette, France.
Stéphanie Morchoisne-BolhyInstitut Jacques Monod, UMR7592, CNRS, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Chiara BertipagliaDepartment of Pathology and Cell Biology, Columbia University, New York, NY, USA.
Richard ValleeDepartment of Pathology and Cell Biology, Columbia University, New York, NY, USA.
Julien DumontInstitut Jacques Monod, UMR7592, CNRS, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Francoise OchsenbeinInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris Sud, Université Paris-Saclay, Gif sur Yvette, France.
Raphael GueroisInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ Paris Sud, Université Paris-Saclay, Gif sur Yvette, France.ORCID 0000-0001-5294-2858
Valérie DoyeInstitut Jacques Monod, UMR7592, CNRS, Université Paris Diderot, Sorbonne Paris Cité, Paris, France valerie.doye@ijm.fr.ORCID 0000-0002-7515-4931
Centre National de la Recherche Scientifique · FRColumbia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cenp-F is a multifaceted protein implicated in cancer and developmental pathologies. The Cenp-F C-terminal region contains overlapping binding sites for numerous proteins that contribute to its functions throughout the cell cycle. Here, we focus on the nuclear pore protein Nup133 that interacts with Cenp-F both at nuclear pores in prophase and at kinetochores in mitosis, and on the kinase Bub1, known to contribute to Cenp-F targeting to kinetochores. By combining

Indexed as

Cell Cycle ProteinsChromosomal Proteins, Non-HistoneHeLa CellsHumansKinetochoresMicrofilament ProteinsMinor Histocompatibility AntigensMitosisNuclear EnvelopeNuclear PoreNuclear Pore Complex ProteinsNuclear ProteinsProtein BindingProtein Serine-Threonine KinasesBUB1 protein, humanCell Cycle Proteinscentromere protein FChromosomal Proteins, Non-HistoneMicrofilament ProteinsMinor Histocompatibility AntigensNuclear Pore Complex ProteinsNuclear ProteinsNUP133 protein, humanProtein Serine-Threonine KinasesCenp‐Fin silico modelingkinetochoresmitosinnuclear pore

Identifiers

PMID29632243
PMCPMC5934770
OpenAlexW2797905940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.