Evidence map›Paper›PMID 29632180›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4.

Sunghyuk Lim, Qinhong Yu, Sean M Gottlieb, Che-Wei Chang, Nathan C Rockwell, Shelley S Martin, Dorte Madsen, J Clark Lagarias, Delmar S Larsen, James B Ames

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Circular dichroism spectroscopy reveals multiple phytochrome photoproducts in equilibrium.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  5. Effects of binding partners on thermal reversion rates of photoswitchable molecules.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Cyanobacteriochromes: A Rainbow of Photoreceptors.Annual review of microbiology · 2024
    Review
  9. Red/green cyanobacteriochromes acquire isomerization from phycocyanobilin to phycoviolobilin.Protein science : a publication of the Protein Society · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Elucidating the origins of phycocyanobilin biosynthesis and phycobiliproteins.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Article
  15. Protein-chromophore interactions controlling photoisomerization in red/green cyanobacteriochromes.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  16. Light- and pH-dependent structural changes in cyanobacteriochrome AnPixJg2.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  17. Review
  18. Article
  19. Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sunghyuk LimDepartment of Chemistry, University of California, Davis, CA 95616.
Qinhong YuDepartment of Chemistry, University of California, Davis, CA 95616.
Sean M GottliebDepartment of Chemistry, University of California, Davis, CA 95616.
Che-Wei ChangDepartment of Chemistry, University of California, Davis, CA 95616.
Nathan C RockwellDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Shelley S MartinDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616.
Dorte MadsenDepartment of Chemistry, University of California, Davis, CA 95616.
J Clark LagariasDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616 jclagarias@ucdavis.edu dlarsen@ucdavis.edu jbames@ucdavis.edu.ORCID 0000-0002-2093-0403
Delmar S LarsenDepartment of Chemistry, University of California, Davis, CA 95616; jclagarias@ucdavis.edu dlarsen@ucdavis.edu jbames@ucdavis.edu.
James B AmesDepartment of Chemistry, University of California, Davis, CA 95616; jclagarias@ucdavis.edu dlarsen@ucdavis.edu jbames@ucdavis.edu.

Funding

MEMBRANE TARGETING CALCIUM SENSORS IN VISIONR01EY012347 · NEI · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI AMES, JAMES B · 1999 to 2023
$6.9M
NEI NIH HHS R01 EY012347
6 · The paper itself

Abstract

Phytochrome photoreceptors control plant growth, development, and the shade avoidance response that limits crop yield in high-density agricultural plantings. Cyanobacteriochromes (CBCRs) are distantly related photosensory proteins that control cyanobacterial metabolism and behavior in response to light. Photoreceptors in both families reversibly photoconvert between two photostates via photoisomerization of linear tetrapyrrole (bilin) chromophores. Spectroscopic and biochemical studies have demonstrated heterogeneity in both photostates, but the structural basis for such heterogeneity remains unclear. We report solution NMR structures for both photostates of the red/green CBCR NpR6012g4 from

Indexed as

Bacterial ProteinsMutagenesis, Site-DirectedNostocPhytochromeProtein DomainsBacterial ProteinsPhytochromebiliproteinlight sensoroptogeneticsphotoacclimationphotoswitch

Identifiers

PMID29632180
PMCPMC5924913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.