ArticleJournal of immunology (Baltimore, Md. : 1950)2018
TCF-1 Inhibits IL-17 Gene Expression To Restrain Th17 Immunity in a Stage-Specific Manner.
Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Selective disruption of RORγt-CBFβ interaction by IMU-935 prevents RORγt-dependent Th17 autoimmunity but not thymocyte development.The Journal of clinical investigation · 2026Article
- Bacterial vaginosis associates with dysfunctional T cells and altered soluble immune factors in the cervicovaginal tract.The Journal of clinical investigation · 2025Observational
- Reshaping CAR-T cells through overexpression of T cell factor 1.Frontiers in immunology · 2025Article
- Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy.Cancer cell · 2024Article
- The dynamic shifts of IL-10-producing Th17 and IL-17-producing Treg in health and disease: a crosstalk between ancient "Yin-Yang" theory and modern immunology.Cell communication and signaling : CCS · 2024Review
- The multifaceted roles of TCF1 in innate and adaptive lymphocytes.Advances in immunology · 2024Review
- TCF-1 Is Required for CD4 T Cell Persistence Functions during AlloImmunity.International journal of molecular sciences · 2023Article
- TCF-1: a maverick in T cell development and function.Nature immunology · 2022Review
- TCF1 in T cell immunity: a broadened frontier.Nature reviews. Immunology · 2022Review
- TProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Upregulation of miR-9 and miR-193b over human Th17 cell differentiation.Molecular genetics & genomic medicine · 2020Article
- Mechanism of Follicular Helper T Cell Differentiation Regulated by Transcription Factors.Journal of immunology research · 2020Review
- TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis.The Journal of experimental medicine · 2019Article
- Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells.The Journal of experimental medicine · 2019Article
- Molecular Control of Follicular Helper T cell Development and Differentiation.Frontiers in immunology · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
T cell factor 1 (TCF-1) is expressed in both developing and mature T cells and has been shown to restrain mature T cell-mediated Th17 responses by inhibiting IL-17 expression. However, it is not clear when TCF-1 is required in vivo to restrain the magnitude of peripheral Th17 responses and what the molecular mechanisms responsible for TCF-1-regulated IL-17 gene expression are. In this study, we showed that conditional deletion of TCF-1 at the early but not later CD4
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