Evidence map›Paper›PMID 29632136›Full record

ArticleDevelopment (Cambridge, England)2018

Slow calcium waves mediate furrow microtubule reorganization and germ plasm compaction in the early zebrafish embryo.

Celeste Eno, Timothy Gomez, Diane C Slusarski, Francisco Pelegri

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Article
  8. Review
  9. Tools to Image Germplasm Dynamics During Early Zebrafish Development.Frontiers in cell and developmental biology · 2021
    Article
  10. Aggregation, segregation, and dispersal of homotypic germ plasm RNPs in the early zebrafish embryo.Developmental dynamics : an official publication of the American Association of Anatomists · 2019
    Article
  11. Calcium Signaling in Vertebrate Development and Its Role in Disease.International journal of molecular sciences · 2018
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Celeste EnoLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI 53706, USA.
Timothy GomezDepartment of Neuroscience, University of Wisconsin - Madison, Madison, WI 53705, USA.ORCID 0000-0002-1515-8228
Diane C SlusarskiDepartment of Biology, The University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0003-3793-8636
Francisco PelegriLaboratory of Genetics, University of Wisconsin - Madison, Madison, WI 53706, USA fjpelegri@wisc.edu.ORCID 0000-0002-0464-7042
University of Wisconsin–Madison · USUniversity of Iowa · US

Funding

Diversity Supplement: Cytokinesis and RNA segregation in zebrafish developmentR01GM065303 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PELEGRI, FRANCISCO J · 2002 to 2023
$4.7M
Molecular mechanisms of growth cone invasionR01NS099405 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2016 to 2019
$1.4M
Wnt/Ca2+ Function in Development and Tumor SuppressionR01CA112369 · NCI · UNIVERSITY OF IOWA · PI SLUSARSKI, DIANE C · 2005 to 2009
$1.1M
Cytokinesis and RNA Segregation in Zebrafish DevelopmentR56GM065303 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PELEGRI, FRANCISCO J · 2007 to 2007
$254k
Germ Plasm Aggregation and Compaction in the Early Zebrafish EmbryoF31GM108449 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI ENO, CELESTE CHLOE · 2014 to 2016
$55k
NCI NIH HHS R01 CA112369NIGMS NIH HHS F31 GM108449NIGMS NIH HHS R01 GM065303NIGMS NIH HHS R56 GM065303
6 · The paper itself

Abstract

Zebrafish germ plasm ribonucleoparticles (RNPs) become recruited to furrows of early zebrafish embryos through their association with astral microtubules ends. During the initiation of cytokinesis, microtubules are remodeled into a furrow microtubule array (FMA), which is thought to be analogous to the mammalian midbody involved in membrane abscission. During furrow maturation, RNPs and FMA tubules transition from their original distribution along the furrow to enrichments at the furrow distal ends, which facilitates germ plasm mass compaction. We show that

Indexed as

ActinsAnimalsBlastomeresBody PatterningCalciumCalcium SignalingCalmodulinCleavage Stage, OvumCytokinesisCytoplasmMicrotubulesRibonucleoproteinsZebrafishActinsCalciumCalmodulinRibonucleoproteinsCalciumF-actinGerm plasmMicrotubulesRibonucleoparticlesZebrafish

Identifiers

PMID29632136
PMCPMC6001370
OpenAlexW2797289960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.