Evidence map›Paper›PMID 29632089›Full record

ArticleJournal of bacteriology2018

Characterization of the Trehalose Utilization Operon in Streptococcus mutans Reveals that the TreR Transcriptional Regulator Is Involved in Stress Response Pathways and Toxin Production.

J L Baker, E L Lindsay, R C Faustoferri, T T To, E L Hendrickson, X He, W Shi, J S McLean, R G Quivey

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. AJournal of bacteriology · 2026
    Review
  2. Article
  3. Uncovering virulence factors inApplied and environmental microbiology · 2023
    Article
  4. Article
  5. Review
  6. Journal of bacteriology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. CariogenicACS infectious diseases · 2020
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

J L BakerDepartment of Genomic Medicine, J. Craig Venter Institute, La Jolla, California, USA.
E L LindsayDepartment of Microbiology & Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
R C FaustoferriCenter for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
T T ToDepartment of Periodontics, School of Dentistry, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-7416-6201
E L HendricksonDepartment of Periodontics, School of Dentistry, University of Washington, Seattle, Washington, USA.
X HeThe Forsyth Institute, Cambridge, Massachusetts, USA.
W ShiThe Forsyth Institute, Cambridge, Massachusetts, USA.
J S McLeanDepartment of Periodontics, School of Dentistry, University of Washington, Seattle, Washington, USA.
R G QuiveyDepartment of Microbiology & Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA Robert_Quivey@urmc.rochester.edu.ORCID 0000-0001-8204-838X
University of Rochester · USUniversity of Washington · USC3J Therapeutics (United States) · USJ. Craig Venter Institute · US

Funding

Comprehensive Training in Inter-Disciplinary Oral Health ResearchT90DE021984 · NIDCR · UNIVERSITY OF WASHINGTON · PI Robert Aaron Cornell · 2012 to 2026
$7.9M
Oxidative Stress Responses in Oral StreptococciR01DE013683 · NIDCR · UNIVERSITY OF ROCHESTER · PI QUIVEY, ROBERT G · 2000 to 2019
$6.2M
Training Program in Oral ScienceT90DE021985 · NIDCR · UNIVERSITY OF ROCHESTER · PI OVITT, CATHERINE, YULE, DAVID I · 2011 to 2021
$5.6M
Making a quantum leap in plaque research with modern sciencesR01DE020102 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HE, XUESONG, MCLEAN, JEFFREY SCOTT · 2010 to 2020
$3.7M
Fitness profiling of the Streptococcus mutans genomeR01DE017425 · NIDCR · UNIVERSITY OF ROCHESTER · PI QUIVEY, ROBERT G · 2007 to 2011
$3.5M
Studying the Protective Effects of Normal Oral FloraR01DE026186 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HE, XUESONG, MCLEAN, JEFFREY SCOTT · 2016 to 2020
$2.1M
Understanding S. Mutans Pathogenesis in a Social and Ecological SettingF32DE026947 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BAKER, JONATHON · 2017 to 2020
$186k
NIDCR NIH HHS F32 DE026947NIDCR NIH HHS R01 DE013683NIDCR NIH HHS R01 DE017425NIDCR NIH HHS R01 DE020102NIDCR NIH HHS R01 DE026186NIDCR NIH HHS T90 DE021984NIDCR NIH HHS T90 DE021985
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, BacterialOperonBacterial ProteinsBacterial ToxinsBacteriocinsBiofilmsRepressor ProteinsSequence DeletionStreptococcus mutansTranscriptional ActivationTrehaloseBacterial ProteinsBacterial ToxinsBacteriocinsRepressor ProteinsTrehalosetrehalose repressor protein, bacteriagene regulationmutacinoxidative stressStreptococcus mutanstrehalose

Identifiers

PMID29632089
PMCPMC5971475
OpenAlexW2796448295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.