Evidence map›Paper›PMID 29632081›Full record

Trial reportBMJ open2018

A randomised controlled trial of a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction and their caregivers: the REACH-HFpEF Pilot Study.

Chim C Lang, Karen Smith, Jennifer Wingham, Victoria Eyre, Colin J Greaves, Fiona C Warren, Colin Green, Kate Jolly, Russell C Davis, Patrick Joseph Doherty and 12 more

Erratum issuedOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 56 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 14 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 14 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Pooled it
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  3. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
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  5. Guideline
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  13. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
  14. Disease management interventions for heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
  15. Trial
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  17. Metacognitive therapy self-help for anxiety-depression: Single-blind randomized feasibility trial in cardiovascular disease.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 10 institutions in 1 country.

Chim C LangSchool of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
Karen SmithSchool of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
Jennifer WinghamInstitute of Health Research, University of Exeter Medical School, Exeter, UK.ORCID 0000-0002-3342-1202
Victoria EyreRe-Cognition Health, Plymouth, UK.ORCID 0000-0003-0927-6815
Colin J GreavesInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
Fiona C WarrenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
Colin GreenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
Kate JollyInstitute for Applied Health Research, University of Birmingham, Birmingham, UK.
Russell C DavisCardiology Department, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
Patrick Joseph DohertyDepartment of Health Sciences, University of York, York, UK.ORCID 0000-0002-1887-0237
Jackie MilesResearch and Development, Anuerin Bevan University Health Board, St Woolos Hospital, Newport, UK.
Nicky BrittenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
Charles AbrahamInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
Robin Van LingenCardiology Department, Royal Cornwall Hospitals NHS Trust, Truro, UK.
Sally J SinghCentre for Exercise and Rehabilitation Science, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK.
Kevin PaulREACH-HF Patient and Public Involvement Group, c/o Research, Development & Innovation, Royal Cornwall Hospitals NHS Trust, Truro, UK.
Melvyn HillsdonSport and Health Sciences, University of Exeter, Exeter, UK.
Susannah SadlerInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
Christopher HaywardPeninsula Clinical Trials Unit, University of Plymouth, Plymouth, UK.
Hayes M DalalInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
Rod S TaylorInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
REACH-HF investigators,
University of Exeter · GBRoyal Cornwall Hospital Trust · GBUniversity of Dundee · GBCambridge Cognition (United Kingdom) · GBGlenfield Hospital · GBSandwell & West Birmingham Hospitals NHS Trust · GBSt Woolos Hospital · GBUniversity of Birmingham · GBUniversity of Plymouth · GBUniversity of York · GB

Funding

Department of Health RP-PG-1210-12004
6 · The paper itself

Abstract

introductionHome-based cardiac rehabilitation may overcome suboptimal rates of participation. The overarching aim of this study was to assess the feasibility and acceptability of the novel Rehabilitation EnAblement in CHronic Hear Failure (REACH-HF) rehabilitation intervention for patients with heart failure with preserved ejection fraction (HFpEF) and their caregivers. METHODS AND

resultsPatients were randomised 1:1 to REACH-HF intervention plus usual care (intervention group) or usual care alone (control group). REACH-HF is a home-based comprehensive self-management rehabilitation programme that comprises patient and carer manuals with supplementary tools, delivered by trained healthcare facilitators over a 12 week period. Patient outcomes were collected by blinded assessors at baseline, 3 months and 6 months postrandomisation and included health-related quality of life (primary) and psychological well-being, exercise capacity, physical activity and HF-related hospitalisation (secondary). Outcomes were also collected in caregivers.We enrolled 50 symptomatic patients with HF from Tayside, Scotland with a left ventricular ejection fraction ≥45% (mean age 73.9 years, 54% female, 100% white British) and 21 caregivers. Study retention (90%) and intervention uptake (92%) were excellent. At 6 months, data from 45 patients showed a potential direction of effect in favour of the intervention group, including the primary outcome of Minnesota Living with Heart Failure Questionnaire total score (between-group mean difference -11.5, 95% CI -22.8 to 0.3). A total of 11 (4 intervention, 7 control) patients experienced a hospital admission over the 6 months of follow-up with 4 (control patients) of these admissions being HF-related. Improvements were seen in a number intervention caregivers' mental health and burden compared with control.

conclusionsOur findings support the feasibility and rationale for delivering the REACH-HF facilitated home-based rehabilitation intervention for patients with HFpEF and their caregivers and progression to a full multicentre randomised clinical trial to test its clinical effectiveness and cost-effectiveness. TRIAL REGISTRATION NUMBER: ISRCTN78539530.

Indexed as

CaregiversHeart FailureSelf CareAdolescentAdultAgedChildFemaleHome Care ServicesHumansMalePilot ProjectsQuality of LifeStroke Volumecardiac rehabilitationcaregiverscomplex interventionheart failureheart failure with preserved ejection fractionrandomised controlled trial

Identifiers

PMID29632081
PMCPMC5893929
OpenAlexW2798034010

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.