Evidence map›Paper›PMID 29632077›Full record

ArticleMolecular and cellular biology2018

IreA Controls Endoplasmic Reticulum Stress-Induced Autophagy and Survival through Homeostasis Recovery.

Eunice Domínguez-Martín, Laura Ongay-Larios, Laura Kawasaki, Olivier Vincent, Gerardo Coello, Roberto Coria, Ricardo Escalante

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Aggrephagy Deficiency in the Placenta: A New Pathogenesis of Preeclampsia.International journal of molecular sciences · 2021
    Review
  5. Article
  6. TheFrontiers in cell and developmental biology · 2021
    Review
  7. Disruption of Placental Homeostasis Leads to Preeclampsia.International journal of molecular sciences · 2020
    Review
  8. The Role of Secretory Pathways inJournal of fungi (Basel, Switzerland) · 2020
    Review
  9. Article
  10. BioMed research international · 2019
    Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Eunice Domínguez-MartínInstituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain.
Laura Ongay-LariosUnidad de Biología Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México City, México.
Laura KawasakiDepartamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México City, México.
Olivier VincentInstituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain.
Gerardo CoelloUnidad de Cómputo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México City, México.
Roberto CoriaDepartamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México City, México rcoria@ifc.unam.mx rescalante@iib.uam.es.
Ricardo EscalanteInstituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain rcoria@ifc.unam.mx rescalante@iib.uam.es.
Universidad Nacional Autónoma de México · MXConsejo Superior de Investigaciones Científicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unfolded protein response (UPR) is an adaptive pathway that restores cellular homeostasis after endoplasmic reticulum (ER) stress. The ER-resident kinase/RNase Ire1 is the only UPR sensor conserved during evolution. Autophagy, a lysosomal degradative pathway, also contributes to the recovery of cell homeostasis after ER stress, but the interplay between these two pathways is still poorly understood. We describe the

Indexed as

Amino Acid SequenceAutophagyDictyosteliumEndoplasmic Reticulum StressGene Expression RegulationGenes, ProtozoanHomeostasisModels, BiologicalMutagenesis, Site-DirectedProtein Serine-Threonine KinasesProtozoan ProteinsRibonucleasesTunicamycinUnfolded Protein ResponseProtein Serine-Threonine KinasesProtozoan ProteinsRibonucleasesTunicamycinautophagyDictyosteliumER stress

Identifiers

PMID29632077
PMCPMC6002696
OpenAlexW2795607021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.