Evidence map›Paper›PMID 29632014›Full record

ArticleAntimicrobial agents and chemotherapy2018

Alterations of Metabolic and Lipid Profiles in Polymyxin-Resistant Pseudomonas aeruginosa.

Mei-Ling Han, Yan Zhu, Darren J Creek, Yu-Wei Lin, Dovile Anderson, Hsin-Hui Shen, Brian Tsuji, Alina D Gutu, Samuel M Moskowitz, Tony Velkov and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  6. Staging of colorectal cancer using lipid biomarkers and machine learning.Metabolomics : Official journal of the Metabolomic Society · 2023
    Article
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  8. Review
  9. Sample Preparation in Microbial Metabolomics: Advances and Challenges.Advances in experimental medicine and biology · 2023
    Article
  10. Article
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  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Bacterial Metabolomics: Sample Preparation Methods.Biochemistry research international · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Mei-Ling HanDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.ORCID 0000-0002-0861-2437
Yan ZhuMonash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Victoria, Australia.
Darren J CreekDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.ORCID 0000-0001-7497-7082
Yu-Wei LinAdvanced Drug Delivery Group, Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.
Dovile AndersonDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Hsin-Hui ShenDepartment of Materials Science and Engineering, Faculty of Engineering, Monash University, Clayton, Victoria, Australia.
Brian TsujiDepartment of Pharmacy Practice, University at Buffalo, Buffalo, New York, USA.
Alina D GutuDepartment of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Samuel M MoskowitzVertex Pharmaceuticals, Boston, Massachusetts, USA.
Tony VelkovDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia Tony.Velkov@unimelb.edu.au Jian.Li@monash.edu.
Jian LiMonash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Victoria, Australia Tony.Velkov@unimelb.edu.au Jian.Li@monash.edu.
Australian Regenerative Medicine Institute · AUMonash University · AUMassachusetts General Hospital · USThe University of Melbourne · AUThe University of Sydney · AUUniversity at Buffalo, State University of New York · USVertex Pharmaceuticals (United States) · US

Funding

New Tricks for 'Old' Drugs: PK/PD of Polymyxin Nonantibiotic CombinationsR01AI111965 · NIAID · MONASH UNIVERSITY · PI LI, JIAN · 2014 to 2018
$4.3M
NIAID NIH HHS R01 AI111965
6 · The paper itself

Abstract

Multidrug-resistant

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug Resistance, BacterialLipid AMetabolomicsMicrobial Sensitivity TestsPhospholipidsPolymyxin BPolymyxinsPseudomonas aeruginosaPseudomonas InfectionsAnti-Bacterial AgentsBacterial ProteinsLipid APhospholipidsPolymyxin BPolymyxinsglycerophospholipidsl-Ara4N biosynthesislipid A modificationmetabolomicsmethionine salvage cyclepolymyxin resistancePseudomonas aeruginosa

Identifiers

PMID29632014
PMCPMC5971563
OpenAlexW2796600167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.