Evidence map›Paper›PMID 29631797›Full record

ArticleAddictive behaviors2018

Diffusion of medication drop-boxes in North Carolina from 2007 to 2016.

Kathleen L Egan, Mark Wolfson, William N Dudley, Vincent T Francisco, Robert W Strack, David L Wyrick, Michael A Perko

Abstract read
In one paragraph

Article in Addictive behaviors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Drug disposal deserts: An assessment of receptacle availability in Kentucky community pharmacies.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Inappropriate opioid prescription after surgery.Lancet (London, England) · 2019
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kathleen L EganDepartment of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida Gainesville, FL, USA. Electronic address: kateegan@ufl.edu.
Mark WolfsonDepartment of Social Science and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC, USA; Center for Research on Substance Use and Addiction, Wake Forest School of Medicine, Winston-Salem, NC, USA.
William N DudleyDepartment of Public Health Education, University of North Carolina at Greensboro, Greensboro, NC, USA.
Vincent T FranciscoDepartment of Applied Behavioral Science, University of Kansas, Lawrence, KS, USA.
Robert W StrackDepartment of Public Health Education, University of North Carolina at Greensboro, Greensboro, NC, USA.
David L WyrickDepartment of Public Health Education, University of North Carolina at Greensboro, Greensboro, NC, USA.
Michael A PerkoDepartment of Public Health Education, University of North Carolina at Greensboro, Greensboro, NC, USA.

Funding

UF Substance Abuse Training Center in Public HealthT32DA035167 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler · 2014 to 2026
$4.8M
NIDA NIH HHS T32 DA035167
6 · The paper itself

Abstract

introductionA permanent drug donation box ("drop-box") is one strategy implemented in communities across the United States to reduce the availability of excess controlled medications, including prescription opioids, for diversion. The objective of this study was to examine correlates of the diffusion and implementation of drop-boxes in North Carolina.

methodsWe assessed the number and location of drop-boxes implemented in North Carolina. Cox proportional hazards models were used to examine covariates associated with drop-box implementation in NC counties (n = 100) between 2007 and 2016.

resultsThere were 311 drop-boxes implemented in 91 (out of 100) counties. Most drop-boxes were in law enforcement agencies (78.8%) and a growing number were in pharmacies (14.5%). Counties with a higher percentage of whites, more educated residents, a substance abuse prevention coalition, higher rates of controlled medications dispensed and prescription opioid overdose, and that were Appalachian were more likely to be early adopters. Rural counties were less likely to have a drop-box. In the multivariate model, only higher rate of controlled medicines dispensed was significant.

conclusionsA growing number of drop-boxes are being implemented in law enforcement offices and pharmacies. Given that communities with higher rates of controlled medication dispensing likely have the highest need for disposal opportunities, it is promising that they are early adopters of drop-boxes. Future research should assess the effectiveness of drop-boxes as they become more widespread in a variety of locations.

Indexed as

Controlled SubstancesLaw EnforcementPharmaciesAnalgesics, OpioidDiffusion of InnovationDrug OverdoseHumansNorth CarolinaPrescription Drug DiversionProportional Hazards ModelsAnalgesics, OpioidControlled SubstancesDisposalDiversionOpioidPrescription drugPrevention

Identifiers

PMID29631797
PMCPMC6091874

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.