Evidence map›Paper›PMID 29631475›Full record

SynthesisThyroid : official journal of the American Thyroid Association2018

Weight Changes After Thyroid Surgery for Patients with Benign Thyroid Nodules and Thyroid Cancer: Population-Based Study and Systematic Review and Meta-Analysis.

Naykky Singh Ospina, Ana Castaneda-Guarderas, Oksana Hamidi, Oscar J Ponce, Wang Zhen, Larry Prokop, Victor M Montori, Juan P Brito

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Thyroid : official journal of the American Thyroid Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Weight Gain After Thyroidectomy: A Systematic Review and Meta-Analysis.The Journal of clinical endocrinology and metabolism · 2021
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Total Thyroidectomy: Resection of Two Organs, Not Just One.Endocrinology and metabolism (Seoul, Korea) · 2024
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Naykky Singh Ospina1 Division of Endocrinology, Diabetes, Metabolism, Department of Medicine, University of Florida , Gainesville, Florida.
Ana Castaneda-Guarderas3 Department of Emergency Medicine, Aventura Hospital and Medical Center , Miami, Florida.
Oksana Hamidi2 Knowledge and Evaluation Research Unit (KER-ENDO), Mayo Clinic , Rochester, Minnesota.
Oscar J Ponce5 Knowledge Synthesis Unit, Mayo Clinic , Rochester, Minnesota.
Wang Zhen5 Knowledge Synthesis Unit, Mayo Clinic , Rochester, Minnesota.
Larry Prokop6 Mayo Medical Libraries, Mayo Clinic , Rochester, Minnesota.
Victor M Montori2 Knowledge and Evaluation Research Unit (KER-ENDO), Mayo Clinic , Rochester, Minnesota.
Juan P Brito2 Knowledge and Evaluation Research Unit (KER-ENDO), Mayo Clinic , Rochester, Minnesota.
Mayo Clinic in Florida · USMayo Clinic · USWinnMed · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
NIA NIH HHS R01 AG034676
6 · The paper itself

Abstract

backgroundA key concern among patients who undergo thyroid surgery is postoperative weight gain. Yet, the impact of thyroid surgery on weight is unclear.

methodsThe population-based Rochester Epidemiology Project was used to examine weight and body mass index (BMI) changes at one, two, and three years of follow-up in (i) patients with thyroid cancer and benign thyroid nodules after thyroid surgery, and (ii) patients with thyroid nodules who did not have surgery. A comprehensive systematic review of the published literature from inception to February 2016 was also conducted. The results were pooled across studies using a random effects model.

resultsA total of 435 patients were identified: 181 patients with thyroid cancer who underwent surgery (group A), 226 patients with benign thyroid nodules without surgery (group B), and 28 patients with benign thyroid nodules undergoing surgery (group C). Small changes in mean weight, BMI, and the number of patients whose weight increased between 5 and 10 kg were similar during each year of follow-up between patients in groups A and B. Furthermore, age >50 years, female sex, baseline BMI >25 kg/m

conclusionsOn average, patients receiving care for thyroid nodules or cancer gain weight, but existing evidence suggests that surgery for these conditions does not contribute significantly to further weight gain. Clinicians and patients can use this information to discuss what to expect after thyroid surgery.

Indexed as

ThyroidectomyBody WeightHumansPostoperative PeriodThyroid NeoplasmsThyroid NoduleWeight Gainthyroid cancerthyroid nodulesTSH suppressionweight

Identifiers

PMID29631475
PMCPMC6117738
OpenAlexW2796898721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.